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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
23.03
Human Site:
Y557
Identified Species:
38.97
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
Y557
R
F
A
S
E
Y
G
Y
Q
S
W
P
S
F
S
Chimpanzee
Pan troglodytes
XP_517370
879
100802
Y557
R
F
A
S
E
Y
G
Y
Q
S
W
P
S
F
S
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
Y752
R
F
A
S
E
Y
G
Y
Q
S
W
P
S
F
S
Dog
Lupus familis
XP_545005
885
101736
Y563
R
F
V
S
E
Y
G
Y
Q
S
W
P
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
Y557
R
L
V
S
E
Y
G
Y
Q
S
W
P
S
F
S
Rat
Rattus norvegicus
Q4FZV0
881
101203
Y557
R
L
V
S
E
Y
G
Y
Q
S
W
P
S
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
S505
Y
G
F
Q
S
W
P
S
F
S
T
L
K
K
V
Frog
Xenopus laevis
NP_001087135
874
101196
F553
R
L
A
S
E
Y
G
F
Q
S
W
P
S
L
S
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
F576
R
F
A
S
E
Y
G
F
Q
S
W
P
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
R574
P
G
I
F
P
R
P
R
F
V
S
E
F
G
F
Honey Bee
Apis mellifera
XP_392850
1110
128827
T757
S
P
S
N
G
L
Y
T
E
Q
Y
N
Y
T
G
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
Q563
C
A
S
E
Y
G
V
Q
S
Y
P
M
K
E
T
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
E407
Y
E
Q
D
E
F
Y
E
L
C
D
E
L
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
P567
T
I
R
A
T
M
P
P
E
G
W
T
I
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
80
86.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
86.6
93.3
N.A.
0
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
36
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
8
0
8
65
0
0
8
15
0
0
15
0
8
0
% E
% Phe:
0
36
8
8
0
8
0
15
15
0
0
0
8
43
8
% F
% Gly:
0
15
0
0
8
8
58
0
0
8
0
0
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
15
8
0
% K
% Leu:
0
22
0
0
0
8
0
0
8
0
0
8
8
15
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
8
0
0
8
0
22
8
0
0
8
58
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
8
58
8
0
0
0
0
0
% Q
% Arg:
58
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
15
58
8
0
0
8
8
65
8
0
58
0
58
% S
% Thr:
8
0
0
0
8
0
0
8
0
0
8
8
0
8
8
% T
% Val:
0
0
22
0
0
0
8
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
65
0
0
0
0
% W
% Tyr:
15
0
0
0
8
58
15
43
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _