KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
20.3
Human Site:
Y705
Identified Species:
34.36
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
Y705
N
E
N
T
F
Y
I
Y
G
V
S
D
L
H
S
Chimpanzee
Pan troglodytes
XP_517370
879
100802
Y705
N
E
N
T
F
Y
I
Y
G
V
S
D
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
Y900
N
E
N
T
F
Y
I
Y
G
V
S
D
L
H
S
Dog
Lupus familis
XP_545005
885
101736
Y711
D
Q
D
L
F
F
I
Y
G
V
S
D
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
Y705
D
E
G
V
F
Y
V
Y
G
V
S
D
L
H
K
Rat
Rattus norvegicus
Q4FZV0
881
101203
Y705
D
E
G
V
F
Y
V
Y
G
V
S
D
L
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
G649
N
G
V
L
Y
I
Y
G
V
S
D
F
H
T
D
Frog
Xenopus laevis
NP_001087135
874
101196
I700
E
D
K
D
V
L
H
I
Y
G
V
S
D
L
T
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
A725
K
G
D
L
L
I
Y
A
V
S
D
R
Q
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
N722
E
K
S
T
D
S
L
N
I
S
L
I
C
D
Q
Honey Bee
Apis mellifera
XP_392850
1110
128827
P936
Y
A
V
E
F
F
A
P
L
I
V
T
Y
Y
I
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
V726
E
T
D
F
N
L
K
V
F
L
L
N
D
N
P
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
P551
C
W
N
I
S
S
F
P
K
P
R
F
A
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
K764
H
V
Y
F
L
L
L
K
L
Y
T
V
S
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
60
N.A.
66.6
66.6
N.A.
N.A.
6.6
0
0
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
13.3
13.3
6.6
N.A.
26.6
26.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
8
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
22
8
22
8
8
0
0
0
0
0
15
43
15
15
8
% D
% Glu:
22
36
0
8
0
0
0
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
15
50
15
8
0
8
0
0
15
0
0
0
% F
% Gly:
0
15
15
0
0
0
0
8
43
8
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
0
8
36
0
% H
% Ile:
0
0
0
8
0
15
29
8
8
8
0
8
0
0
8
% I
% Lys:
8
8
8
0
0
0
8
8
8
0
0
0
0
0
22
% K
% Leu:
0
0
0
22
15
22
15
0
15
8
15
0
43
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
29
0
29
0
8
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
0
8
0
8
15
0
0
0
22
43
8
8
22
29
% S
% Thr:
0
8
0
29
0
0
0
0
0
0
8
8
0
8
8
% T
% Val:
0
8
15
15
8
0
15
8
15
43
15
8
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
36
15
43
8
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _