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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANBA
All Species:
21.21
Human Site:
Y856
Identified Species:
35.9
UniProt:
O00462
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00462
NP_005899.3
879
100895
Y856
K
T
R
T
I
L
F
Y
P
W
E
P
T
S
K
Chimpanzee
Pan troglodytes
XP_517370
879
100802
Y856
K
T
R
T
I
L
F
Y
P
W
E
P
T
S
K
Rhesus Macaque
Macaca mulatta
XP_001101549
1074
122458
Y1051
K
T
R
T
I
L
F
Y
P
W
E
P
T
S
K
Dog
Lupus familis
XP_545005
885
101736
Y862
R
T
R
T
V
L
F
Y
P
W
Q
P
T
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I4
879
100812
Y856
K
K
L
S
V
L
F
Y
P
W
K
P
T
S
K
Rat
Rattus norvegicus
Q4FZV0
881
101203
L856
I
K
K
E
L
S
V
L
F
Y
P
W
K
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420666
822
94668
P800
R
K
V
V
I
F
Y
P
W
E
P
T
S
V
E
Frog
Xenopus laevis
NP_001087135
874
101196
Y851
K
T
K
T
V
Y
F
Y
P
W
Q
T
T
S
V
Zebra Danio
Brachydanio rerio
XP_002664183
901
102422
I876
L
S
K
K
T
T
V
I
F
G
A
W
R
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649436
908
103501
Q873
L
S
E
N
G
F
M
Q
T
E
P
M
H
V
V
Honey Bee
Apis mellifera
XP_392850
1110
128827
H1087
N
T
K
K
I
L
F
H
A
C
D
V
T
T
S
Nematode Worm
Caenorhab. elegans
Q93324
900
103960
L877
Q
R
L
R
K
I
R
L
I
A
K
F
E
V
D
Sea Urchin
Strong. purpuratus
XP_001186463
724
81612
A702
T
F
S
L
C
P
K
A
I
T
T
T
Y
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q75W54
944
107642
I915
G
E
S
M
S
F
K
I
S
F
A
A
P
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
76.5
80.4
N.A.
75.7
75.2
N.A.
N.A.
64.2
58.1
53.8
N.A.
34.6
29.9
33.3
39.2
Protein Similarity:
100
99.5
79.2
87.6
N.A.
85.8
86.6
N.A.
N.A.
77.5
74.2
70.4
N.A.
52.2
47.2
54.1
52.3
P-Site Identity:
100
100
100
80
N.A.
66.6
0
N.A.
N.A.
6.6
60
6.6
N.A.
0
33.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
N.A.
33.3
80
20
N.A.
6.6
60
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
15
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
8
8
8
0
0
0
0
0
15
22
0
8
0
8
% E
% Phe:
0
8
0
0
0
22
50
0
15
8
0
8
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
36
8
0
15
15
0
0
0
0
0
0
% I
% Lys:
36
22
29
15
8
0
15
0
0
0
15
0
8
0
36
% K
% Leu:
15
0
15
8
8
43
0
15
0
0
0
0
0
0
8
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
43
0
22
36
8
8
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
15
0
0
0
0
% Q
% Arg:
15
8
29
8
0
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
15
15
8
8
8
0
0
8
0
0
0
8
50
8
% S
% Thr:
8
43
0
36
8
8
0
0
8
8
8
22
50
22
15
% T
% Val:
0
0
8
8
22
0
15
0
0
0
0
8
0
22
15
% V
% Trp:
0
0
0
0
0
0
0
0
8
43
0
15
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
43
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _