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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGRN
All Species:
7.58
Human Site:
S1292
Identified Species:
18.52
UniProt:
O00468
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00468
NP_940978.2
2045
214846
S1292
T
P
R
A
P
H
P
S
H
T
S
Q
P
V
A
Chimpanzee
Pan troglodytes
XP_520844
1301
134556
C668
E
E
S
G
S
A
H
C
V
C
P
M
L
T
C
Rhesus Macaque
Macaca mulatta
XP_001088755
1817
191152
R1166
L
L
Y
N
G
N
A
R
G
K
D
F
L
A
L
Dog
Lupus familis
XP_536713
1943
205449
S1184
T
Q
W
A
L
Y
P
S
H
T
S
R
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
A2ASQ1
1950
207520
Y1176
T
P
R
V
Y
P
S
Y
T
S
R
P
V
G
R
Rat
Rattus norvegicus
P25304
1959
208627
H1185
T
P
R
V
Y
P
S
H
T
S
R
P
V
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513262
657
68583
S24
V
P
A
A
D
G
R
S
A
R
C
L
C
P
A
Chicken
Gallus gallus
P31696
2073
224100
H1310
L
R
Q
D
T
V
G
H
P
S
A
K
L
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391941
2397
265210
T1674
K
V
Y
E
N
I
G
T
N
H
G
F
L
G
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791472
1397
148917
S764
S
N
G
E
G
C
P
S
V
C
N
C
N
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
74.7
79.5
N.A.
76
77.2
N.A.
23.1
63.4
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
22.8
Protein Similarity:
100
59.1
77.3
84.2
N.A.
82.3
83
N.A.
26.1
75.1
N.A.
N.A.
N.A.
N.A.
36
N.A.
35.1
P-Site Identity:
100
0
0
60
N.A.
20
20
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
0
6.6
73.3
N.A.
26.6
26.6
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
30
0
10
10
0
10
0
10
0
0
20
30
% A
% Cys:
0
0
0
0
0
10
0
10
0
20
10
10
10
0
20
% C
% Asp:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
10
0
20
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
10
10
20
10
20
0
10
0
10
0
0
30
10
% G
% His:
0
0
0
0
0
10
10
20
20
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
20
10
0
0
10
0
0
0
0
0
0
10
40
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
10
10
10
0
0
10
0
10
0
10
0
0
% N
% Pro:
0
40
0
0
10
20
30
0
10
0
10
20
20
20
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
30
0
0
0
10
10
0
10
20
10
0
0
20
% R
% Ser:
10
0
10
0
10
0
20
40
0
30
20
0
0
0
0
% S
% Thr:
40
0
0
0
10
0
0
10
20
20
0
0
0
10
0
% T
% Val:
10
10
0
20
0
10
0
0
20
0
0
0
20
20
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
20
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _