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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGRN
All Species:
7.58
Human Site:
S218
Identified Species:
18.52
UniProt:
O00468
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00468
NP_940978.2
2045
214846
S218
G
S
D
A
S
T
Y
S
N
E
C
E
L
Q
R
Chimpanzee
Pan troglodytes
XP_520844
1301
134556
Rhesus Macaque
Macaca mulatta
XP_001088755
1817
191152
C191
G
A
D
Y
P
G
E
C
Q
L
L
R
R
A
C
Dog
Lupus familis
XP_536713
1943
205449
Q192
A
D
Y
P
S
E
C
Q
L
L
R
L
A
C
T
Cat
Felis silvestris
Mouse
Mus musculus
A2ASQ1
1950
207520
Q192
V
D
Y
P
S
E
C
Q
L
L
R
H
A
C
A
Rat
Rattus norvegicus
P25304
1959
208627
Q192
V
D
Y
P
S
E
C
Q
L
L
S
H
A
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513262
657
68583
Chicken
Gallus gallus
P31696
2073
224100
S220
G
S
D
Y
S
T
Y
S
N
E
C
E
L
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391941
2397
265210
T518
G
S
D
N
V
T
Y
T
N
Y
C
H
L
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791472
1397
148917
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
74.7
79.5
N.A.
76
77.2
N.A.
23.1
63.4
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
22.8
Protein Similarity:
100
59.1
77.3
84.2
N.A.
82.3
83
N.A.
26.1
75.1
N.A.
N.A.
N.A.
N.A.
36
N.A.
35.1
P-Site Identity:
100
0
13.3
6.6
N.A.
6.6
6.6
N.A.
0
80
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
0
P-Site Similarity:
100
0
20
6.6
N.A.
6.6
6.6
N.A.
0
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
0
0
0
0
0
30
10
20
% A
% Cys:
0
0
0
0
0
0
30
10
0
0
30
0
0
30
10
% C
% Asp:
0
30
40
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
30
10
0
0
20
0
20
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
40
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
0
0
0
0
0
0
0
0
30
40
10
10
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
30
0
0
0
0
0
0
% N
% Pro:
0
0
0
30
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
30
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
20
10
10
10
10
% R
% Ser:
0
30
0
0
50
0
0
20
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
30
0
10
0
0
0
0
0
0
10
% T
% Val:
20
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
30
20
0
0
30
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _