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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGRN All Species: 8.79
Human Site: T1285 Identified Species: 21.48
UniProt: O00468 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00468 NP_940978.2 2045 214846 T1285 R L P S S A V T P R A P H P S
Chimpanzee Pan troglodytes XP_520844 1301 134556 E661 E F G A R C V E E S G S A H C
Rhesus Macaque Macaca mulatta XP_001088755 1817 191152 L1159 A L E L Q G L L L Y N G N A R
Dog Lupus familis XP_536713 1943 205449 T1177 A H L P P A G T Q W A L Y P S
Cat Felis silvestris
Mouse Mus musculus A2ASQ1 1950 207520 T1169 R L S A S S V T P R V Y P S Y
Rat Rattus norvegicus P25304 1959 208627 T1178 R L P A S S V T P R V Y P S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513262 657 68583 V17 C S F G S S C V P A A D G R S
Chicken Gallus gallus P31696 2073 224100 L1303 A A T T A H I L R Q D T V G H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391941 2397 265210 K1667 N M P T N Y S K V Y E N I G T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791472 1397 148917 S757 N Q T E A L G S N G E G C P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.4 74.7 79.5 N.A. 76 77.2 N.A. 23.1 63.4 N.A. N.A. N.A. N.A. 23.4 N.A. 22.8
Protein Similarity: 100 59.1 77.3 84.2 N.A. 82.3 83 N.A. 26.1 75.1 N.A. N.A. N.A. N.A. 36 N.A. 35.1
P-Site Identity: 100 6.6 6.6 33.3 N.A. 46.6 53.3 N.A. 26.6 0 N.A. N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 13.3 20 40 N.A. 60 66.6 N.A. 33.3 26.6 N.A. N.A. N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 0 30 20 20 0 0 0 10 30 0 10 10 0 % A
% Cys: 10 0 0 0 0 10 10 0 0 0 0 0 10 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 10 0 10 10 0 0 0 10 10 0 20 0 0 0 0 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 20 0 0 10 10 20 10 20 0 % G
% His: 0 10 0 0 0 10 0 0 0 0 0 0 10 10 20 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 40 10 10 0 10 10 20 10 0 0 10 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 0 10 0 0 0 10 0 10 10 10 0 0 % N
% Pro: 0 0 30 10 10 0 0 0 40 0 0 10 20 30 0 % P
% Gln: 0 10 0 0 10 0 0 0 10 10 0 0 0 0 0 % Q
% Arg: 30 0 0 0 10 0 0 0 10 30 0 0 0 10 10 % R
% Ser: 0 10 10 10 40 30 10 10 0 10 0 10 0 20 40 % S
% Thr: 0 0 20 20 0 0 0 40 0 0 0 10 0 0 10 % T
% Val: 0 0 0 0 0 0 40 10 10 0 20 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 20 0 20 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _