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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGRN All Species: 0.91
Human Site: T724 Identified Species: 2.22
UniProt: O00468 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00468 NP_940978.2 2045 214846 T724 V C G S D G V T Y S T E C E L
Chimpanzee Pan troglodytes XP_520844 1301 134556 R141 R P R C S C D R V T C D G A Y
Rhesus Macaque Macaca mulatta XP_001088755 1817 191152 A638 S R Q E L S V A A Q G A C R G
Dog Lupus familis XP_536713 1943 205449 T640 S R R E L Y V T A Q G A C R G
Cat Felis silvestris
Mouse Mus musculus A2ASQ1 1950 207520 Q642 Q E L Y V A A Q G A C R G P T
Rat Rattus norvegicus P25304 1959 208627 A640 S Q Q E L Y V A A Q G A C R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513262 657 68583
Chicken Gallus gallus P31696 2073 224100 V724 P V C G S D D V T Y A N E C E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391941 2397 265210 D1107 D P P L V D A D G K E Y D C G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791472 1397 148917 V237 Q Q K S V T V V F Q G L C D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.4 74.7 79.5 N.A. 76 77.2 N.A. 23.1 63.4 N.A. N.A. N.A. N.A. 23.4 N.A. 22.8
Protein Similarity: 100 59.1 77.3 84.2 N.A. 82.3 83 N.A. 26.1 75.1 N.A. N.A. N.A. N.A. 36 N.A. 35.1
P-Site Identity: 100 0 13.3 20 N.A. 0 13.3 N.A. 0 0 N.A. N.A. N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 13.3 13.3 20 N.A. 6.6 13.3 N.A. 0 0 N.A. N.A. N.A. N.A. 0 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 20 20 30 10 10 30 0 10 0 % A
% Cys: 0 10 10 10 0 10 0 0 0 0 20 0 50 20 0 % C
% Asp: 10 0 0 0 10 20 20 10 0 0 0 10 10 10 0 % D
% Glu: 0 10 0 30 0 0 0 0 0 0 10 10 10 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 0 0 20 0 40 0 20 0 40 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 0 10 10 30 0 0 0 0 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 20 10 0 0 0 0 0 0 0 0 0 0 10 10 % P
% Gln: 20 20 20 0 0 0 0 10 0 40 0 0 0 0 0 % Q
% Arg: 10 20 20 0 0 0 0 10 0 0 0 10 0 30 0 % R
% Ser: 30 0 0 20 20 10 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 20 10 10 10 0 0 0 10 % T
% Val: 10 10 0 0 30 0 50 20 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 20 0 0 10 10 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _