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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGRN
All Species:
3.94
Human Site:
T845
Identified Species:
9.63
UniProt:
O00468
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00468
NP_940978.2
2045
214846
T845
T
D
G
R
S
G
C
T
P
C
S
C
D
P
Q
Chimpanzee
Pan troglodytes
XP_520844
1301
134556
A252
L
G
R
E
I
Q
V
A
R
K
G
P
C
D
R
Rhesus Macaque
Macaca mulatta
XP_001088755
1817
191152
R749
C
D
P
Q
G
A
V
R
D
D
C
E
Q
M
T
Dog
Lupus familis
XP_536713
1943
205449
R751
C
D
P
R
G
A
V
R
D
D
C
E
Q
M
T
Cat
Felis silvestris
Mouse
Mus musculus
A2ASQ1
1950
207520
D753
P
R
G
A
V
R
D
D
C
E
Q
M
T
G
L
Rat
Rattus norvegicus
P25304
1959
208627
R751
C
D
P
R
G
A
V
R
D
D
C
E
Q
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513262
657
68583
Chicken
Gallus gallus
P31696
2073
224100
T845
T
D
S
K
S
G
C
T
P
C
N
C
D
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391941
2397
265210
I1227
S
E
G
H
Q
G
C
I
P
C
G
C
S
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791472
1397
148917
E348
C
V
C
T
P
C
P
E
V
F
T
P
V
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
74.7
79.5
N.A.
76
77.2
N.A.
23.1
63.4
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
22.8
Protein Similarity:
100
59.1
77.3
84.2
N.A.
82.3
83
N.A.
26.1
75.1
N.A.
N.A.
N.A.
N.A.
36
N.A.
35.1
P-Site Identity:
100
0
6.6
13.3
N.A.
6.6
13.3
N.A.
0
73.3
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
P-Site Similarity:
100
6.6
13.3
13.3
N.A.
6.6
13.3
N.A.
0
86.6
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
30
0
10
0
0
0
0
0
0
0
% A
% Cys:
40
0
10
0
0
10
30
0
10
30
30
30
10
10
0
% C
% Asp:
0
50
0
0
0
0
10
10
30
30
0
0
20
10
0
% D
% Glu:
0
10
0
10
0
0
0
10
0
10
0
30
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
10
30
0
30
30
0
0
0
0
20
0
0
10
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
30
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
30
0
10
0
10
0
30
0
0
20
0
20
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
10
0
30
0
10
% Q
% Arg:
0
10
10
30
0
10
0
30
10
0
0
0
0
0
10
% R
% Ser:
10
0
10
0
20
0
0
0
0
0
10
0
10
0
0
% S
% Thr:
20
0
0
10
0
0
0
20
0
0
10
0
10
0
30
% T
% Val:
0
10
0
0
10
0
40
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _