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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEIS1 All Species: 33.94
Human Site: S196 Identified Species: 62.22
UniProt: O00470 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00470 NP_002389.1 390 43016 S196 D R E G G S K S D S E D I T R
Chimpanzee Pan troglodytes XP_001167056 378 41729 S196 D R E G G S K S D S E D I T R
Rhesus Macaque Macaca mulatta XP_001092069 378 41703 S196 D R E G G S K S D S E D I T R
Dog Lupus familis XP_852744 322 35460 E158 V L R F H L L E L E K V H E L
Cat Felis silvestris
Mouse Mus musculus Q60954 390 42984 S196 D R E G G S K S D S E D V T R
Rat Rattus norvegicus NP_001128174 390 42968 S196 D R E G G S K S D S E D V T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001132949 390 42940 S196 D R E G G S K S D S E D I T R
Frog Xenopus laevis P79937 390 42868 S196 D R D G G S K S D S E D L T R
Zebra Danio Brachydanio rerio NP_571968 388 42824 S194 D R E G G S K S D S E E I T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46339 487 52766 S248 D V R P P S S S L S Y G G A M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N5D6 564 60870 G270 E N A G V M G G H P M E G S S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q1PFD1 290 33005 S126 E I A G E G S S K V Y T G L A
Baker's Yeast Sacchar. cerevisiae P53147 276 31239 I112 T G E R N Y I I T V G G P P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 95.6 82.3 N.A. 99.7 99.4 N.A. N.A. 96.9 94.6 95.3 N.A. 50.9 N.A. 35.4 N.A.
Protein Similarity: 100 96.4 96.4 82.5 N.A. 100 100 N.A. N.A. 98.4 98.2 97.1 N.A. 61.1 N.A. 45 N.A.
P-Site Identity: 100 100 100 0 N.A. 93.3 93.3 N.A. N.A. 100 86.6 93.3 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.5 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. 37.6 36.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 70 0 8 0 0 0 0 0 62 0 0 54 0 0 0 % D
% Glu: 16 0 62 0 8 0 0 8 0 8 62 16 0 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 77 62 8 8 8 0 0 8 16 24 0 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 8 8 0 0 0 0 39 0 0 % I
% Lys: 0 0 0 0 0 0 62 0 8 0 8 0 0 0 0 % K
% Leu: 0 8 0 0 0 8 8 0 16 0 0 0 8 8 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 8 0 0 0 0 8 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 62 16 8 0 0 0 0 0 0 0 0 0 0 62 % R
% Ser: 0 0 0 0 0 70 16 77 0 70 0 0 0 8 8 % S
% Thr: 8 0 0 0 0 0 0 0 8 0 0 8 0 62 0 % T
% Val: 8 8 0 0 8 0 0 0 0 16 0 8 16 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _