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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS1
All Species:
35.45
Human Site:
S245
Identified Species:
65
UniProt:
O00470
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00470
NP_002389.1
390
43016
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Chimpanzee
Pan troglodytes
XP_001167056
378
41729
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Rhesus Macaque
Macaca mulatta
XP_001092069
378
41703
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Dog
Lupus familis
XP_852744
322
35460
L207
D
I
T
R
S
A
N
L
T
D
Q
P
S
W
N
Cat
Felis silvestris
Mouse
Mus musculus
Q60954
390
42984
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Rat
Rattus norvegicus
NP_001128174
390
42968
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001132949
390
42940
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Frog
Xenopus laevis
P79937
390
42868
S245
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Zebra Danio
Brachydanio rerio
NP_571968
388
42824
S243
S
H
S
G
D
N
S
S
E
Q
G
D
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
T297
S
L
N
P
S
E
L
T
Y
D
G
R
W
C
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
T319
S
T
A
G
A
S
Q
T
L
L
P
I
A
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PFD1
290
33005
S175
K
I
I
S
S
G
L
S
Q
L
S
L
F
D
G
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
I161
G
Y
T
N
P
Q
P
I
S
I
S
R
G
K
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
82.3
N.A.
99.7
99.4
N.A.
N.A.
96.9
94.6
95.3
N.A.
50.9
N.A.
35.4
N.A.
Protein Similarity:
100
96.4
96.4
82.5
N.A.
100
100
N.A.
N.A.
98.4
98.2
97.1
N.A.
61.1
N.A.
45
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
62
0
0
0
0
16
0
62
0
8
62
% D
% Glu:
0
0
0
0
0
8
0
0
62
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
70
0
8
0
0
0
0
70
0
70
0
8
% G
% His:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
8
0
0
0
0
8
0
8
0
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
16
8
8
16
0
8
0
62
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
8
0
62
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
8
0
8
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
8
62
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
8
% R
% Ser:
77
0
62
8
24
8
62
70
8
0
16
0
8
0
8
% S
% Thr:
0
8
16
0
0
0
0
16
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _