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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEIS1 All Species: 28.18
Human Site: T22 Identified Species: 51.67
UniProt: O00470 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00470 NP_002389.1 390 43016 T22 D G V G I P S T M Y G D P H A
Chimpanzee Pan troglodytes XP_001167056 378 41729 T22 D G V G I P S T M Y G D P H A
Rhesus Macaque Macaca mulatta XP_001092069 378 41703 T22 D G V G I P S T M Y G D P H A
Dog Lupus familis XP_852744 322 35460 V17 H Y G G M D G V G I P S T M Y
Cat Felis silvestris
Mouse Mus musculus Q60954 390 42984 T22 D G V G I P S T M Y G D P H A
Rat Rattus norvegicus NP_001128174 390 42968 T22 D G V G I P S T M Y G D P H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001132949 390 42940 T22 E G V G I P T T M Y G D P H G
Frog Xenopus laevis P79937 390 42868 S22 D G V G L P S S M Y G D P H A
Zebra Danio Brachydanio rerio NP_571968 388 42824 M22 G V G I P S T M Y G D P H A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46339 487 52766 S41 P G L Q G L P S H H S P H M T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N5D6 564 60870 N44 R D H N E Q F N D G Y G P P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q1PFD1 290 33005
Baker's Yeast Sacchar. cerevisiae P53147 276 31239
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 95.6 82.3 N.A. 99.7 99.4 N.A. N.A. 96.9 94.6 95.3 N.A. 50.9 N.A. 35.4 N.A.
Protein Similarity: 100 96.4 96.4 82.5 N.A. 100 100 N.A. N.A. 98.4 98.2 97.1 N.A. 61.1 N.A. 45 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. N.A. 80 86.6 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 93.3 100 13.3 N.A. 26.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.5 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. 37.6 36.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 54 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 8 0 0 0 8 0 0 8 0 8 54 0 0 0 % D
% Glu: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 62 16 62 8 0 8 0 8 16 54 8 0 0 8 % G
% His: 8 0 8 0 0 0 0 0 8 8 0 0 16 54 0 % H
% Ile: 0 0 0 8 47 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 8 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 8 54 0 0 0 0 16 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 54 8 0 0 0 8 16 62 8 8 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 47 16 0 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 16 47 0 0 0 0 8 0 8 % T
% Val: 0 8 54 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 8 54 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _