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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS1
All Species:
30.3
Human Site:
T220
Identified Species:
55.56
UniProt:
O00470
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00470
NP_002389.1
390
43016
T220
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Chimpanzee
Pan troglodytes
XP_001167056
378
41729
T220
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001092069
378
41703
T220
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Dog
Lupus familis
XP_852744
322
35460
P182
S
C
L
K
G
K
M
P
I
D
L
V
I
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60954
390
42984
T220
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Rat
Rattus norvegicus
NP_001128174
390
42968
T220
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001132949
390
42940
T220
W
N
R
D
H
D
G
T
A
S
T
R
S
G
G
Frog
Xenopus laevis
P79937
390
42868
A220
W
S
R
D
H
D
D
A
A
S
I
R
S
G
G
Zebra Danio
Brachydanio rerio
NP_571968
388
42824
T218
W
N
R
D
H
D
D
T
A
S
T
R
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
S272
G
S
T
P
G
P
L
S
Q
Q
P
P
A
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
S294
A
A
A
A
S
S
S
S
S
S
N
Q
A
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PFD1
290
33005
S150
S
L
E
E
A
I
I
S
Q
L
N
S
V
R
R
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
Q136
I
S
T
P
N
F
Y
Q
E
Q
R
L
A
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
82.3
N.A.
99.7
99.4
N.A.
N.A.
96.9
94.6
95.3
N.A.
50.9
N.A.
35.4
N.A.
Protein Similarity:
100
96.4
96.4
82.5
N.A.
100
100
N.A.
N.A.
98.4
98.2
97.1
N.A.
61.1
N.A.
45
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
93.3
80
100
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
93.3
86.6
100
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
8
0
0
8
62
0
0
0
24
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
62
54
0
0
8
0
0
0
8
24
% D
% Glu:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
16
0
8
0
0
0
0
0
0
70
62
% G
% His:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
8
0
8
0
8
0
8
0
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
0
8
0
0
8
8
8
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
54
0
0
8
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
0
16
0
8
0
8
0
0
8
8
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
16
16
0
8
0
8
0
% Q
% Arg:
0
0
62
0
0
0
0
0
0
0
8
62
0
8
8
% R
% Ser:
16
24
0
0
8
8
8
24
8
70
0
8
62
0
0
% S
% Thr:
0
0
16
0
0
0
0
54
0
0
54
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _