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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS1
All Species:
30
Human Site:
Y11
Identified Species:
55
UniProt:
O00470
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00470
NP_002389.1
390
43016
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Chimpanzee
Pan troglodytes
XP_001167056
378
41729
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Rhesus Macaque
Macaca mulatta
XP_001092069
378
41703
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Dog
Lupus familis
XP_852744
322
35460
Cat
Felis silvestris
Mouse
Mus musculus
Q60954
390
42984
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Rat
Rattus norvegicus
NP_001128174
390
42968
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001132949
390
42940
Y11
R
Y
D
E
L
P
H
Y
G
G
M
E
G
V
G
Frog
Xenopus laevis
P79937
390
42868
Y11
R
Y
D
D
L
P
H
Y
G
G
M
D
G
V
G
Zebra Danio
Brachydanio rerio
NP_571968
388
42824
Y11
R
Y
E
D
I
P
H
Y
G
M
D
G
V
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
G30
A
M
Y
D
P
H
A
G
H
R
P
P
G
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
K33
D
L
D
T
S
S
I
K
R
E
K
R
D
H
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PFD1
290
33005
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
82.3
N.A.
99.7
99.4
N.A.
N.A.
96.9
94.6
95.3
N.A.
50.9
N.A.
35.4
N.A.
Protein Similarity:
100
96.4
96.4
82.5
N.A.
100
100
N.A.
N.A.
98.4
98.2
97.1
N.A.
61.1
N.A.
45
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
86.6
100
46.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
100
100
60
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
62
62
0
0
0
0
0
0
8
47
8
0
0
% D
% Glu:
0
0
8
8
0
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
62
54
0
8
62
8
54
% G
% His:
0
0
0
0
0
8
62
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
8
0
0
54
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
54
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
62
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
62
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
62
8
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _