KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEIS1
All Species:
40.61
Human Site:
Y299
Identified Species:
74.44
UniProt:
O00470
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00470
NP_002389.1
390
43016
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Chimpanzee
Pan troglodytes
XP_001167056
378
41729
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Rhesus Macaque
Macaca mulatta
XP_001092069
378
41703
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Dog
Lupus familis
XP_852744
322
35460
D252
S
E
Q
G
D
G
L
D
N
S
V
A
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60954
390
42984
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Rat
Rattus norvegicus
NP_001128174
390
42968
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001132949
390
42940
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Frog
Xenopus laevis
P79937
390
42868
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Zebra Danio
Brachydanio rerio
NP_571968
388
42824
Y297
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46339
487
52766
Y392
F
Q
H
L
T
H
P
Y
P
S
E
D
Q
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N5D6
564
60870
Y419
F
H
N
L
T
H
P
Y
P
S
E
E
Q
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PFD1
290
33005
W220
S
V
A
I
L
R
A
W
L
F
Q
H
F
L
H
Baker's Yeast
Sacchar. cerevisiae
P53147
276
31239
V206
S
N
L
P
K
A
T
V
S
I
L
N
K
W
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
95.6
82.3
N.A.
99.7
99.4
N.A.
N.A.
96.9
94.6
95.3
N.A.
50.9
N.A.
35.4
N.A.
Protein Similarity:
100
96.4
96.4
82.5
N.A.
100
100
N.A.
N.A.
98.4
98.2
97.1
N.A.
61.1
N.A.
45
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
N.A.
86.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
77
70
0
0
0
% E
% Phe:
77
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
70
0
0
77
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
8
77
77
% K
% Leu:
0
0
8
77
8
0
8
0
8
0
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
77
0
77
0
0
0
0
8
0
% P
% Gln:
0
70
8
0
0
0
0
0
0
0
8
0
77
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
0
0
0
0
0
0
8
85
0
0
8
0
8
% S
% Thr:
0
0
0
0
77
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _