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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC17A3
All Species:
16.06
Human Site:
S187
Identified Species:
32.12
UniProt:
O00476
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00476
NP_006623.2
420
46106
S187
S
Y
P
W
I
S
T
S
E
K
E
Y
I
I
S
Chimpanzee
Pan troglodytes
XP_518284
498
54233
S265
S
Y
P
W
I
S
T
S
E
K
E
Y
I
I
S
Rhesus Macaque
Macaca mulatta
XP_001083774
498
54349
S265
S
Y
P
W
I
S
T
S
E
K
E
Y
I
T
S
Dog
Lupus familis
XP_535908
493
53547
K260
P
W
I
N
V
T
E
K
E
Y
I
I
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SZA1
478
51947
R244
H
H
P
C
I
S
V
R
E
K
E
H
I
T
S
Rat
Rattus norvegicus
Q62795
465
51332
S231
N
H
P
Y
M
S
S
S
E
K
D
Y
I
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519993
502
53998
R265
S
H
P
F
I
S
A
R
E
K
D
Y
I
T
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC8
576
63887
Y273
I
S
E
E
E
R
K
Y
I
E
E
S
I
G
E
Zebra Danio
Brachydanio rerio
Q1L8X9
590
64796
Y286
I
S
E
E
E
R
N
Y
I
E
T
S
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7S5
529
58354
R265
S
H
P
T
I
D
E
R
E
K
K
Y
I
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34644
576
63090
K276
P
T
I
S
Q
E
E
K
I
F
I
E
D
A
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX78
541
59595
S321
P
K
D
D
P
D
L
S
E
E
E
K
K
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
78.7
60.2
N.A.
43.9
39.1
N.A.
36.2
N.A.
26.2
25.7
N.A.
26.2
N.A.
23.7
N.A.
Protein Similarity:
100
83.9
81.5
71.1
N.A.
59.6
58
N.A.
52.1
N.A.
41.1
41.6
N.A.
44
N.A.
39.5
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
53.3
53.3
N.A.
60
N.A.
13.3
6.6
N.A.
46.6
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
66.6
93.3
N.A.
80
N.A.
20
13.3
N.A.
60
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
17
0
0
0
0
17
0
9
0
9
% D
% Glu:
0
0
17
17
17
9
25
0
75
25
50
9
0
0
17
% E
% Phe:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% G
% His:
9
34
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
17
0
17
0
50
0
0
0
25
0
17
9
75
17
17
% I
% Lys:
0
9
0
0
0
0
9
17
0
59
9
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% N
% Pro:
25
0
59
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
17
0
25
0
0
0
0
0
0
0
% R
% Ser:
42
17
0
9
0
50
9
42
0
0
0
17
9
9
50
% S
% Thr:
0
9
0
9
0
9
25
0
0
0
9
0
0
34
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
9
0
25
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
0
9
0
0
0
17
0
9
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _