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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC17A3
All Species:
17.58
Human Site:
S375
Identified Species:
35.15
UniProt:
O00476
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00476
NP_006623.2
420
46106
S375
T
V
S
G
F
L
L
S
Q
D
P
E
F
G
W
Chimpanzee
Pan troglodytes
XP_518284
498
54233
S453
T
V
S
G
F
L
L
S
Q
D
P
E
F
G
W
Rhesus Macaque
Macaca mulatta
XP_001083774
498
54349
S453
T
V
S
G
F
L
L
S
Q
D
P
E
F
G
W
Dog
Lupus familis
XP_535908
493
53547
N448
T
V
S
G
F
L
L
N
Q
D
S
E
F
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5SZA1
478
51947
S433
T
T
T
G
F
L
I
S
Q
D
S
E
S
G
W
Rat
Rattus norvegicus
Q62795
465
51332
N420
T
L
A
G
L
I
L
N
Q
D
P
E
Y
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519993
502
53998
S454
T
V
V
G
F
L
T
S
Q
D
A
L
T
G
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC8
576
63887
K461
L
I
V
G
A
M
T
K
H
K
T
R
E
E
W
Zebra Danio
Brachydanio rerio
Q1L8X9
590
64796
K474
L
I
V
G
A
L
T
K
H
K
T
R
L
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7S5
529
58354
S454
I
A
A
G
H
L
I
S
D
P
S
K
P
M
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34644
576
63090
A464
F
V
T
E
A
F
T
A
H
S
K
H
G
W
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX78
541
59595
Q508
A
A
T
G
Y
I
L
Q
R
G
S
W
D
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
78.7
60.2
N.A.
43.9
39.1
N.A.
36.2
N.A.
26.2
25.7
N.A.
26.2
N.A.
23.7
N.A.
Protein Similarity:
100
83.9
81.5
71.1
N.A.
59.6
58
N.A.
52.1
N.A.
41.1
41.6
N.A.
44
N.A.
39.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
66.6
53.3
N.A.
66.6
N.A.
13.3
20
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
66.6
N.A.
26.6
26.6
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
25
0
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
59
0
0
9
9
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
50
9
17
0
% E
% Phe:
9
0
0
0
50
9
0
0
0
0
0
0
34
0
0
% F
% Gly:
0
0
0
92
0
0
0
0
0
9
0
0
9
50
0
% G
% His:
0
0
0
0
9
0
0
0
25
0
0
9
0
0
0
% H
% Ile:
9
17
0
0
0
17
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
0
17
9
9
0
0
0
% K
% Leu:
17
9
0
0
9
67
50
0
0
0
0
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
34
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
59
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
17
0
0
0
% R
% Ser:
0
0
34
0
0
0
0
50
0
9
34
0
9
0
0
% S
% Thr:
59
9
25
0
0
0
34
0
0
0
17
0
9
0
9
% T
% Val:
0
50
25
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
75
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _