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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A3 All Species: 10.3
Human Site: S69 Identified Species: 20.61
UniProt: O00476 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00476 NP_006623.2 420 46106 S69 T M V A M V N S T S P Q S Q L
Chimpanzee Pan troglodytes XP_518284 498 54233 S69 T M V A M V N S T S P Q S Q L
Rhesus Macaque Macaca mulatta XP_001083774 498 54349 S69 T M V A M V N S T S P Q S Q F
Dog Lupus familis XP_535908 493 53547 H69 A M V N T T D H Q F Q F N G S
Cat Felis silvestris
Mouse Mus musculus Q5SZA1 478 51947 G114 I P S G Y L A G I F G A K Q I
Rat Rattus norvegicus Q62795 465 51332 I92 V F L G M V V I Q V P V G Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519993 502 53998 L141 A G L L G G K L V A G A G L L
Chicken Gallus gallus
Frog Xenopus laevis Q6INC8 576 63887 K101 N T V Y K G N K L V I E Q A Q
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 S89 S G L G F C I S F G I R C N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 H71 A I V A M V N H T A I K S G E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34644 576 63090 R87 F M I S F G I R C N F G A A K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 M159 M S I A I L P M S Q E Y N W S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 78.7 60.2 N.A. 43.9 39.1 N.A. 36.2 N.A. 26.2 25.7 N.A. 26.2 N.A. 23.7 N.A.
Protein Similarity: 100 83.9 81.5 71.1 N.A. 59.6 58 N.A. 52.1 N.A. 41.1 41.6 N.A. 44 N.A. 39.5 N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 6.6 26.6 N.A. 6.6 N.A. 13.3 13.3 N.A. 46.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 20 33.3 N.A. 20 N.A. 20 33.3 N.A. 66.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 42 0 0 9 0 0 17 0 17 9 17 0 % A
% Cys: 0 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 9 % E
% Phe: 9 9 0 0 17 0 0 0 9 17 9 9 0 0 9 % F
% Gly: 0 17 0 25 9 25 0 9 0 9 17 9 17 17 0 % G
% His: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % H
% Ile: 9 9 17 0 9 0 17 9 9 0 25 0 0 0 9 % I
% Lys: 0 0 0 0 9 0 9 9 0 0 0 9 9 0 9 % K
% Leu: 0 0 25 9 0 17 0 9 9 0 0 0 0 9 42 % L
% Met: 9 42 0 0 42 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 0 42 0 0 9 0 0 17 9 0 % N
% Pro: 0 9 0 0 0 0 9 0 0 0 34 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 9 9 25 9 34 9 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % R
% Ser: 9 9 9 9 0 0 0 34 9 25 0 0 34 0 17 % S
% Thr: 25 9 0 0 9 9 0 0 34 0 0 0 0 0 0 % T
% Val: 9 0 50 0 0 42 9 0 9 17 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 9 9 0 0 0 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _