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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR5A2
All Species:
27.27
Human Site:
S218
Identified Species:
46.15
UniProt:
O00482
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00482
NP_003813.1
541
61331
S218
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Chimpanzee
Pan troglodytes
XP_520248
771
84677
P452
A
P
D
Y
V
L
P
P
S
L
H
A
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001110281
541
61327
S218
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Dog
Lupus familis
XP_547371
548
62005
S225
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P45448
560
64002
S237
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Rat
Rattus norvegicus
Q9QWM1
560
63886
S237
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Wallaby
Macropus eugenll
Q95L87
463
51850
H176
V
P
M
A
V
P
T
H
G
P
L
A
G
Y
L
Platypus
Ornith. anatinus
XP_001505652
637
72367
S314
S
A
I
Q
N
I
H
S
A
S
K
G
L
P
L
Chicken
Gallus gallus
O42101
501
57084
S206
P
F
V
T
S
P
I
S
M
T
M
P
P
H
G
Frog
Xenopus laevis
P70033
435
49986
S149
S
N
Q
P
S
P
V
S
T
P
S
S
S
R
S
Zebra Danio
Brachydanio rerio
Q9PU65
477
54037
L191
S
S
N
R
S
V
E
L
N
G
Y
T
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33244
1027
108400
S706
S
S
V
G
N
G
N
S
S
N
G
S
S
N
G
Honey Bee
Apis mellifera
XP_001122182
878
92065
A562
P
D
S
S
P
S
P
A
A
V
A
A
G
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791919
487
54933
P199
K
G
P
I
M
N
I
P
Q
P
M
S
L
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
99.6
88.1
N.A.
86.9
86.9
57.4
80.6
90
23.6
27.5
N.A.
26.1
28.2
N.A.
45.4
Protein Similarity:
100
52.1
99.8
89.7
N.A.
90.3
90.5
67.8
83
91.1
41.2
44.7
N.A.
35.8
40.2
N.A.
61
P-Site Identity:
100
0
100
100
N.A.
100
100
6.6
100
6.6
13.3
13.3
N.A.
20
6.6
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
13.3
100
26.6
20
40
N.A.
53.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
0
8
0
0
0
8
50
0
8
22
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
0
0
8
8
8
43
15
0
15
% G
% His:
0
0
0
0
0
0
43
8
0
0
8
0
0
8
0
% H
% Ile:
0
0
43
8
0
43
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
8
0
8
8
0
50
8
58
% L
% Met:
0
0
8
0
8
0
0
0
8
0
15
0
0
0
0
% M
% Asn:
0
8
8
0
50
8
8
0
8
8
0
0
0
8
0
% N
% Pro:
15
15
8
8
8
22
15
15
0
22
0
8
15
50
8
% P
% Gln:
0
0
8
43
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
65
15
8
8
22
8
0
65
15
43
8
22
15
0
8
% S
% Thr:
0
0
0
8
0
0
8
0
8
8
0
8
8
0
0
% T
% Val:
8
0
15
0
15
8
8
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _