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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR5A2 All Species: 27.27
Human Site: S218 Identified Species: 46.15
UniProt: O00482 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00482 NP_003813.1 541 61331 S218 S A I Q N I H S A S K G L P L
Chimpanzee Pan troglodytes XP_520248 771 84677 P452 A P D Y V L P P S L H A P E P
Rhesus Macaque Macaca mulatta XP_001110281 541 61327 S218 S A I Q N I H S A S K G L P L
Dog Lupus familis XP_547371 548 62005 S225 S A I Q N I H S A S K G L P L
Cat Felis silvestris
Mouse Mus musculus P45448 560 64002 S237 S A I Q N I H S A S K G L P L
Rat Rattus norvegicus Q9QWM1 560 63886 S237 S A I Q N I H S A S K G L P L
Wallaby Macropus eugenll Q95L87 463 51850 H176 V P M A V P T H G P L A G Y L
Platypus Ornith. anatinus XP_001505652 637 72367 S314 S A I Q N I H S A S K G L P L
Chicken Gallus gallus O42101 501 57084 S206 P F V T S P I S M T M P P H G
Frog Xenopus laevis P70033 435 49986 S149 S N Q P S P V S T P S S S R S
Zebra Danio Brachydanio rerio Q9PU65 477 54037 L191 S S N R S V E L N G Y T T A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P33244 1027 108400 S706 S S V G N G N S S N G S S N G
Honey Bee Apis mellifera XP_001122182 878 92065 A562 P D S S P S P A A V A A G L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791919 487 54933 P199 K G P I M N I P Q P M S L P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 99.6 88.1 N.A. 86.9 86.9 57.4 80.6 90 23.6 27.5 N.A. 26.1 28.2 N.A. 45.4
Protein Similarity: 100 52.1 99.8 89.7 N.A. 90.3 90.5 67.8 83 91.1 41.2 44.7 N.A. 35.8 40.2 N.A. 61
P-Site Identity: 100 0 100 100 N.A. 100 100 6.6 100 6.6 13.3 13.3 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. 100 100 13.3 100 26.6 20 40 N.A. 53.3 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 43 0 8 0 0 0 8 50 0 8 22 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 0 8 0 0 8 8 8 43 15 0 15 % G
% His: 0 0 0 0 0 0 43 8 0 0 8 0 0 8 0 % H
% Ile: 0 0 43 8 0 43 15 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 8 0 8 8 0 50 8 58 % L
% Met: 0 0 8 0 8 0 0 0 8 0 15 0 0 0 0 % M
% Asn: 0 8 8 0 50 8 8 0 8 8 0 0 0 8 0 % N
% Pro: 15 15 8 8 8 22 15 15 0 22 0 8 15 50 8 % P
% Gln: 0 0 8 43 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 65 15 8 8 22 8 0 65 15 43 8 22 15 0 8 % S
% Thr: 0 0 0 8 0 0 8 0 8 8 0 8 8 0 0 % T
% Val: 8 0 15 0 15 8 8 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _