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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR5A2 All Species: 26.36
Human Site: T242 Identified Species: 44.62
UniProt: O00482 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00482 NP_003813.1 541 61331 T242 Y D R S P F V T S P I S M T M
Chimpanzee Pan troglodytes XP_520248 771 84677 A476 G P L G D F G A P A L P M A V
Rhesus Macaque Macaca mulatta XP_001110281 541 61327 T242 Y D R S P F V T S P I S M T M
Dog Lupus familis XP_547371 548 62005 T249 Y D R S P F V T S P I S M T M
Cat Felis silvestris
Mouse Mus musculus P45448 560 64002 T261 Y D R S P F V T S P I S M T M
Rat Rattus norvegicus Q9QWM1 560 63886 T261 Y D R S P F V T S P I S M T M
Wallaby Macropus eugenll Q95L87 463 51850 Y200 K S E Y P E P Y A S P H E P A
Platypus Ornith. anatinus XP_001505652 637 72367 T338 Y D R S P F V T S P I S M T M
Chicken Gallus gallus O42101 501 57084 K230 H F P S R A I K S E Y P D P Y
Frog Xenopus laevis P70033 435 49986 P173 R D Q Y L G T P G P T H Y Q Y
Zebra Danio Brachydanio rerio Q9PU65 477 54037 P215 A Q H Y Q F L P H L F G Y A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P33244 1027 108400 N730 T S G G G G G N N A G G G G G
Honey Bee Apis mellifera XP_001122182 878 92065 S586 Q H Q L I A P S S Q P N I S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791919 487 54933 T223 I Q P L N Y T T S T A P I Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 99.6 88.1 N.A. 86.9 86.9 57.4 80.6 90 23.6 27.5 N.A. 26.1 28.2 N.A. 45.4
Protein Similarity: 100 52.1 99.8 89.7 N.A. 90.3 90.5 67.8 83 91.1 41.2 44.7 N.A. 35.8 40.2 N.A. 61
P-Site Identity: 100 13.3 100 100 N.A. 100 100 6.6 100 13.3 13.3 6.6 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 13.3 100 26.6 20 13.3 N.A. 6.6 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 15 0 8 8 15 8 0 0 15 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 0 8 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 8 0 0 8 0 0 % E
% Phe: 0 8 0 0 0 58 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 8 15 8 15 15 0 8 0 8 15 8 8 8 % G
% His: 8 8 8 0 0 0 0 0 8 0 0 15 0 0 0 % H
% Ile: 8 0 0 0 8 0 8 0 0 0 43 0 15 0 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 15 8 0 8 0 0 8 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 43 % M
% Asn: 0 0 0 0 8 0 0 8 8 0 0 8 0 0 0 % N
% Pro: 0 8 15 0 50 0 15 15 8 50 15 22 0 15 8 % P
% Gln: 8 15 15 0 8 0 0 0 0 8 0 0 0 15 0 % Q
% Arg: 8 0 43 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 0 50 0 0 0 8 65 8 0 43 0 8 0 % S
% Thr: 8 0 0 0 0 0 15 50 0 8 8 0 0 43 0 % T
% Val: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 43 0 0 22 0 8 0 8 0 0 8 0 15 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _