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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD14
All Species:
38.18
Human Site:
T177
Identified Species:
64.62
UniProt:
O00487
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00487
NP_005796.1
310
34577
T177
L
G
H
E
P
R
Q
T
T
S
N
L
G
H
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535931
299
33365
T177
L
G
H
E
P
R
Q
T
T
S
N
L
G
H
L
Cat
Felis silvestris
Mouse
Mus musculus
O35864
334
37530
E198
K
G
Y
K
P
P
D
E
G
P
S
E
Y
Q
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLM9
332
37492
E196
K
G
Y
K
P
P
D
E
G
P
S
E
Y
Q
T
Zebra Danio
Brachydanio rerio
Q6PC30
334
37563
E196
K
G
Y
K
P
P
D
E
G
P
S
E
Y
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3H2
308
34382
T175
L
G
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Honey Bee
Apis mellifera
XP_393559
311
34598
T178
L
G
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Nematode Worm
Caenorhab. elegans
O76577
312
34577
T179
L
N
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Sea Urchin
Strong. purpuratus
XP_780027
311
34633
T178
L
G
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Poplar Tree
Populus trichocarpa
XP_002302444
309
34528
T177
L
G
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Maize
Zea mays
NP_001137003
307
34389
T175
L
G
Q
E
P
R
Q
T
T
S
N
V
G
H
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT08
308
34335
T176
L
G
Q
E
P
R
Q
T
T
S
N
L
G
H
L
Baker's Yeast
Sacchar. cerevisiae
P43588
306
34380
T173
N
N
L
E
P
R
Q
T
T
S
N
T
G
L
L
Red Bread Mold
Neurospora crassa
Q7RXX8
336
37444
T190
K
P
F
A
A
T
N
T
T
T
G
D
G
Q
S
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.5
N.A.
31.1
N.A.
N.A.
N.A.
N.A.
30.7
30.8
N.A.
88.3
89.7
75.3
92.6
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
51.7
N.A.
N.A.
N.A.
N.A.
51.5
51.2
N.A.
93.2
94.8
83.9
94.8
P-Site Identity:
100
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
93.3
93.3
86.6
93.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
33.3
N.A.
93.3
93.3
86.6
93.3
Percent
Protein Identity:
80
80
N.A.
79.6
65.1
26.7
Protein Similarity:
87.4
87.7
N.A.
87.4
76.7
46.4
P-Site Identity:
93.3
86.6
N.A.
93.3
66.6
20
P-Site Similarity:
93.3
93.3
N.A.
93.3
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
22
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
72
0
0
0
22
0
0
0
22
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
79
0
0
0
0
0
0
22
0
8
0
79
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
65
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
29
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
65
0
8
0
0
0
0
0
0
0
0
58
0
8
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
15
0
0
0
0
8
0
0
0
72
0
0
0
0
% N
% Pro:
0
8
0
0
93
22
0
0
0
22
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
72
0
0
0
0
0
0
29
0
% Q
% Arg:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
72
22
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
79
79
8
0
8
0
0
22
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
0
0
0
0
0
0
0
22
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _