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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD14 All Species: 14.85
Human Site: T20 Identified Species: 25.13
UniProt: O00487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00487 NP_005796.1 310 34577 T20 G L G Q G P P T D A P A V D T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535931 299 33365 T20 G L G Q G P P T D A P A V D T
Cat Felis silvestris
Mouse Mus musculus O35864 334 37530 P44 Q E I L A A K P W T K D H H Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6GLM9 332 37492 P42 Q E I L A A K P W T K D H H Y
Zebra Danio Brachydanio rerio Q6PC30 334 37563 P42 Q E I L A A K P W T K D H H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3H2 308 34382 T18 M P Q A A P P T D A P V V D T
Honey Bee Apis mellifera XP_393559 311 34598 S21 L S Q G P P P S D A P V V D T
Nematode Worm Caenorhab. elegans O76577 312 34577 Q22 G T F G A N P Q D S N Q V D T
Sea Urchin Strong. purpuratus XP_780027 311 34633 S21 L G Q G T T P S D G P V V D T
Poplar Tree Populus trichocarpa XP_002302444 309 34528 P20 G A L G H P P P D S P T L D S
Maize Zea mays NP_001137003 307 34389 T18 S G M G Q P P T D S P L L D S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT08 308 34335 P19 G G L G H A S P D S P T L D T
Baker's Yeast Sacchar. cerevisiae P43588 306 34380 A16 M N S K V G S A D T G R D D T
Red Bread Mold Neurospora crassa Q7RXX8 336 37444 P33 K A V V N S R P W T N D H K Y
Conservation
Percent
Protein Identity: 100 N.A. N.A. 94.5 N.A. 31.1 N.A. N.A. N.A. N.A. 30.7 30.8 N.A. 88.3 89.7 75.3 92.6
Protein Similarity: 100 N.A. N.A. 95.8 N.A. 51.7 N.A. N.A. N.A. N.A. 51.5 51.2 N.A. 93.2 94.8 83.9 94.8
P-Site Identity: 100 N.A. N.A. 100 N.A. 0 N.A. N.A. N.A. N.A. 0 0 N.A. 60 53.3 40 40
P-Site Similarity: 100 N.A. N.A. 100 N.A. 0 N.A. N.A. N.A. N.A. 0 0 N.A. 60 60 46.6 46.6
Percent
Protein Identity: 80 80 N.A. 79.6 65.1 26.7
Protein Similarity: 87.4 87.7 N.A. 87.4 76.7 46.4
P-Site Identity: 40 40 N.A. 33.3 20 0
P-Site Similarity: 60 60 N.A. 46.6 26.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 8 36 29 0 8 0 29 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 72 0 0 29 8 72 0 % D
% Glu: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 22 15 43 15 8 0 0 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 15 0 0 0 0 0 0 0 29 22 0 % H
% Ile: 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 8 0 0 22 0 0 0 22 0 0 8 0 % K
% Leu: 15 15 15 22 0 0 0 0 0 0 0 8 22 0 0 % L
% Met: 15 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 8 0 0 0 0 15 0 0 0 0 % N
% Pro: 0 8 0 0 8 43 58 43 0 0 58 0 0 0 0 % P
% Gln: 22 0 22 15 8 0 0 8 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % R
% Ser: 8 8 8 0 0 8 15 15 0 29 0 0 0 0 15 % S
% Thr: 0 8 0 0 8 8 0 29 0 36 0 15 0 0 58 % T
% Val: 0 0 8 8 8 0 0 0 0 0 0 22 43 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _