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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD14 All Species: 55.45
Human Site: Y112 Identified Species: 93.85
UniProt: O00487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00487 NP_005796.1 310 34577 Y112 P E M V V G W Y H S H P G F G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535931 299 33365 Y112 P E M V V G W Y H S H P G F G
Cat Felis silvestris
Mouse Mus musculus O35864 334 37530 Y137 L E N A I G W Y H S H P G Y G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6GLM9 332 37492 Y135 L E N A I G W Y H S H P G Y G
Zebra Danio Brachydanio rerio Q6PC30 334 37563 Y135 L E N A I G W Y H S H P G Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3H2 308 34382 Y110 P E M V V G W Y H S H P G F G
Honey Bee Apis mellifera XP_393559 311 34598 Y113 P E M V V G W Y H S H P G F G
Nematode Worm Caenorhab. elegans O76577 312 34577 Y114 P E M V V G W Y H S H P G F G
Sea Urchin Strong. purpuratus XP_780027 311 34633 Y113 P E M V V G W Y H S H P G F G
Poplar Tree Populus trichocarpa XP_002302444 309 34528 Y112 P E M V V G W Y H S H P G F G
Maize Zea mays NP_001137003 307 34389 Y110 P E M V V G W Y H S H P G F G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT08 308 34335 Y111 P E M V V G W Y H S H P G F G
Baker's Yeast Sacchar. cerevisiae P43588 306 34380 Y108 D Q M V V G W Y H S H P G F G
Red Bread Mold Neurospora crassa Q7RXX8 336 37444 Y126 L E N V I G W Y H S H P G Y G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 94.5 N.A. 31.1 N.A. N.A. N.A. N.A. 30.7 30.8 N.A. 88.3 89.7 75.3 92.6
Protein Similarity: 100 N.A. N.A. 95.8 N.A. 51.7 N.A. N.A. N.A. N.A. 51.5 51.2 N.A. 93.2 94.8 83.9 94.8
P-Site Identity: 100 N.A. N.A. 100 N.A. 66.6 N.A. N.A. N.A. N.A. 66.6 66.6 N.A. 100 100 100 100
P-Site Similarity: 100 N.A. N.A. 100 N.A. 80 N.A. N.A. N.A. N.A. 80 80 N.A. 100 100 100 100
Percent
Protein Identity: 80 80 N.A. 79.6 65.1 26.7
Protein Similarity: 87.4 87.7 N.A. 87.4 76.7 46.4
P-Site Identity: 100 100 N.A. 100 86.6 73.3
P-Site Similarity: 100 100 N.A. 100 93.3 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 72 0 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 0 100 0 100 % G
% His: 0 0 0 0 0 0 0 0 100 0 100 0 0 0 0 % H
% Ile: 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 65 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 79 72 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 29 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _