KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF593
All Species:
11.89
Human Site:
T132
Identified Species:
29.06
UniProt:
O00488
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00488
NP_056955.2
134
15199
T132
T
E
V
P
E
M
D
T
S
T
_
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086340
173
19599
T171
T
E
V
P
E
M
D
T
S
T
_
_
_
_
_
Dog
Lupus familis
XP_544486
182
20097
T177
T
E
V
P
E
M
V
T
T
P
C
M
T
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB42
134
15129
T132
T
D
I
P
E
M
D
T
S
T
_
_
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006307
133
15318
A131
D
E
V
V
E
M
E
A
S
S
_
_
_
_
_
Frog
Xenopus laevis
NP_001088318
127
15125
G109
A
E
R
A
G
G
M
G
S
Y
I
P
P
K
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W3Y0
162
18904
K130
K
E
D
V
V
A
G
K
R
I
R
V
E
V
V
Honey Bee
Apis mellifera
XP_001120173
143
16916
E129
T
N
Y
N
M
D
V
E
P
E
T
S
S
Q
V
Nematode Worm
Caenorhab. elegans
Q9U239
128
14551
V124
Q
P
E
I
P
I
P
V
V
A
E
T
_
_
_
Sea Urchin
Strong. purpuratus
XP_797052
140
16486
D130
T
Q
Q
P
T
E
Q
D
V
T
M
N
E
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
71.6
65.3
N.A.
90.3
N.A.
N.A.
N.A.
65.6
46.2
N.A.
N.A.
37.6
38.4
33.5
42.8
Protein Similarity:
100
N.A.
72.8
67
N.A.
95.5
N.A.
N.A.
N.A.
74.6
66.4
N.A.
N.A.
52.4
56.6
52.9
60
P-Site Identity:
100
N.A.
100
53.8
N.A.
80
N.A.
N.A.
N.A.
50
13.3
N.A.
N.A.
6.6
6.6
0
20
P-Site Similarity:
100
N.A.
100
61.5
N.A.
100
N.A.
N.A.
N.A.
70
20
N.A.
N.A.
6.6
6.6
8.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
10
0
10
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
10
10
0
0
10
30
10
0
0
0
0
0
0
0
% D
% Glu:
0
60
10
0
50
10
10
10
0
10
10
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
10
0
0
0
10
10
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
10
50
10
0
0
0
10
10
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
0
50
10
0
10
0
10
10
0
10
10
0
0
% P
% Gln:
10
10
10
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
50
10
0
10
10
0
0
% S
% Thr:
60
0
0
0
10
0
0
40
10
40
10
10
10
0
0
% T
% Val:
0
0
40
20
10
0
20
10
20
0
0
10
0
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
40
40
50
60
60
% _