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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF593
All Species:
12.42
Human Site:
T78
Identified Species:
30.37
UniProt:
O00488
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00488
NP_056955.2
134
15199
T78
I
D
S
T
N
L
K
T
H
F
R
S
K
D
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086340
173
19599
T117
I
D
S
A
N
L
K
T
H
F
R
S
K
D
H
Dog
Lupus familis
XP_544486
182
20097
T123
I
D
S
A
T
L
K
T
H
F
R
S
K
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB42
134
15129
T78
I
D
S
A
N
L
K
T
H
F
R
S
K
D
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006307
133
15318
E77
V
D
L
T
S
M
K
E
H
F
R
S
K
V
H
Frog
Xenopus laevis
NP_001088318
127
15125
L55
N
Q
E
L
D
Y
Q
L
P
G
N
G
Q
H
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W3Y0
162
18904
A76
I
D
D
T
A
M
Q
A
H
F
R
T
K
V
H
Honey Bee
Apis mellifera
XP_001120173
143
16916
D75
I
N
D
T
A
L
Q
D
H
F
T
T
K
V
H
Nematode Worm
Caenorhab. elegans
Q9U239
128
14551
L70
V
D
E
K
T
R
Q
L
H
R
K
T
K
L
H
Sea Urchin
Strong. purpuratus
XP_797052
140
16486
A76
V
D
E
G
A
M
K
A
H
F
R
Q
K
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
71.6
65.3
N.A.
90.3
N.A.
N.A.
N.A.
65.6
46.2
N.A.
N.A.
37.6
38.4
33.5
42.8
Protein Similarity:
100
N.A.
72.8
67
N.A.
95.5
N.A.
N.A.
N.A.
74.6
66.4
N.A.
N.A.
52.4
56.6
52.9
60
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
93.3
N.A.
N.A.
N.A.
60
0
N.A.
N.A.
53.3
46.6
26.6
46.6
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
93.3
N.A.
N.A.
N.A.
80
26.6
N.A.
N.A.
73.3
66.6
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
30
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
80
20
0
10
0
0
10
0
0
0
0
0
40
0
% D
% Glu:
0
0
30
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
90
0
0
0
0
10
90
% H
% Ile:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
60
0
0
0
10
0
90
0
0
% K
% Leu:
0
0
10
10
0
50
0
20
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
30
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
40
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
10
70
0
0
0
0
% R
% Ser:
0
0
40
0
10
0
0
0
0
0
0
50
0
0
0
% S
% Thr:
0
0
0
40
20
0
0
40
0
0
10
30
0
10
0
% T
% Val:
30
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _