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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN5
All Species:
33.03
Human Site:
S201
Identified Species:
80.74
UniProt:
O00501
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00501
NP_001124333.1
218
23147
S201
L
S
F
P
V
K
Y
S
A
P
R
R
P
T
A
Chimpanzee
Pan troglodytes
XP_530408
219
23200
S202
L
S
F
P
V
K
Y
S
A
P
R
R
P
T
A
Rhesus Macaque
Macaca mulatta
XP_001104943
218
23049
S201
L
S
F
P
V
K
Y
S
A
P
R
R
P
T
A
Dog
Lupus familis
XP_543546
302
32016
S285
F
S
F
P
V
K
Y
S
A
P
R
R
P
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O54942
218
23036
S201
F
S
F
P
V
K
Y
S
A
P
R
R
P
T
A
Rat
Rattus norvegicus
Q9JKD6
218
23054
S201
F
S
F
P
V
K
Y
S
A
P
R
R
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511784
216
22376
S199
L
G
F
P
V
R
Y
S
A
P
R
R
P
A
P
Chicken
Gallus gallus
NP_989532
216
23162
S199
T
S
F
P
V
K
Y
S
A
P
R
R
P
T
S
Frog
Xenopus laevis
NP_001085820
216
22996
S199
S
N
L
P
V
K
Y
S
A
P
R
M
P
T
S
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
R191
Q
C
P
K
N
E
G
R
A
Y
S
V
K
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
67.5
N.A.
91.7
91.2
N.A.
70.6
70.1
62.3
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.1
68.8
N.A.
94
93.5
N.A.
82.5
82.5
77
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
73.3
86.6
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
80
93.3
80
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
100
0
0
0
0
10
60
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
30
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
80
0
0
0
0
0
0
10
0
0
% K
% Leu:
40
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
90
0
0
0
0
0
90
0
0
80
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
90
80
0
0
0
% R
% Ser:
10
70
0
0
0
0
0
90
0
0
10
0
0
0
30
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
10
80
0
% T
% Val:
0
0
0
0
90
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
90
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _