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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA3 All Species: 35.15
Human Site: S336 Identified Species: 51.56
UniProt: O00505 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00505 NP_002258.2 521 57811 S336 S H F P N L L S H P K E K I N
Chimpanzee Pan troglodytes XP_001156682 529 58696 S336 S H F P N L L S H P K E K I N
Rhesus Macaque Macaca mulatta XP_001097222 521 57902 T336 S H F P A L L T H P K E K I N
Dog Lupus familis XP_534112 497 55001 S312 S H F P N L L S H P K E K I N
Cat Felis silvestris
Mouse Mus musculus O35344 521 57754 S336 S H F P N L L S H P K E K I N
Rat Rattus norvegicus Q56R16 536 60281 G346 P C L L H L L G S P K E S V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513797 569 62801 T384 S H F P N L L T H P K E K I N
Chicken Gallus gallus Q5ZML1 538 60176 S348 Q S L L H L L S S P K E S I K
Frog Xenopus laevis P52170 522 57670 R338 S V L P Q L L R H Q K P S I Q
Zebra Danio Brachydanio rerio Q503E9 536 59774 S346 P C L L H L L S S P K E S I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 Q334 P R L G L L L Q H N K S N I V
Honey Bee Apis mellifera XP_395967 516 57341 T334 S Y F P N L L T H T R E K I C
Nematode Worm Caenorhab. elegans Q19969 514 56144 A329 R F M P G L L A H Y K E K I N
Sea Urchin Strong. purpuratus XP_001178060 510 56437 D327 Q H F P A L L D H A K D K I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 T336 P C L A N L L T Q N H K K S I
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 S351 P A L R L L L S S P K E N I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 85.8 94.8 N.A. 99.2 47.9 N.A. 86.4 48.1 48.6 48.8 N.A. 45 69 62 69.4
Protein Similarity: 100 98.4 92.1 95 N.A. 99.4 66 N.A. 88.2 63.7 67.4 66 N.A. 63 81.1 73.6 80.2
P-Site Identity: 100 100 86.6 100 N.A. 100 33.3 N.A. 93.3 46.6 46.6 46.6 N.A. 33.3 66.6 60 66.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 46.6 N.A. 100 53.3 46.6 53.3 N.A. 33.3 86.6 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 43.8 47.2 N.A.
Protein Similarity: N.A. N.A. N.A. 62.5 62.1 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 13 0 0 7 0 7 0 0 0 0 0 % A
% Cys: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % E
% Phe: 0 7 50 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 0 0 7 0 0 0 0 0 0 0 % G
% His: 0 44 0 0 19 0 0 0 69 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 88 7 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 88 7 63 0 19 % K
% Leu: 0 0 44 19 13 100 100 0 0 0 0 0 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 44 0 0 0 0 13 0 0 13 0 50 % N
% Pro: 32 0 0 63 0 0 0 0 0 63 0 7 0 0 0 % P
% Gln: 13 0 0 0 7 0 0 7 7 7 0 0 0 0 7 % Q
% Arg: 7 7 0 7 0 0 0 7 0 0 7 0 0 0 7 % R
% Ser: 50 7 0 0 0 0 0 44 25 0 0 7 25 7 0 % S
% Thr: 0 0 0 0 0 0 0 25 0 7 0 0 0 0 0 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _