KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAD1
All Species:
10.91
Human Site:
T388
Identified Species:
40
UniProt:
O00515
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00515
NP_005549.2
517
57131
T388
K
K
E
N
S
E
T
T
L
T
R
S
A
S
M
Chimpanzee
Pan troglodytes
XP_001146774
517
57161
T388
K
K
E
N
S
E
T
T
L
T
R
S
A
S
M
Rhesus Macaque
Macaca mulatta
XP_001108686
516
56913
T387
K
K
D
N
S
E
T
T
L
T
R
S
A
S
M
Dog
Lupus familis
XP_849490
477
51627
M349
P
R
T
I
S
F
R
M
S
P
R
R
D
N
P
Cat
Felis silvestris
Mouse
Mus musculus
P57016
528
58846
P399
R
K
D
N
S
E
T
P
L
T
R
S
A
S
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517359
362
40602
T234
R
A
E
A
E
E
V
T
S
P
T
Q
S
T
Q
Chicken
Gallus gallus
P12957
771
88729
Q617
E
F
L
N
K
S
A
Q
K
S
G
M
K
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
94.3
51.2
N.A.
63.8
N.A.
N.A.
26.5
22
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
96.7
63
N.A.
75.5
N.A.
N.A.
43.9
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
73.3
N.A.
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
N.A.
N.A.
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
0
0
15
0
0
0
0
0
58
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
15
0
43
0
15
72
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
15
0
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
43
58
0
0
15
0
0
0
15
0
0
0
15
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
58
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
43
% M
% Asn:
0
0
0
72
0
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
15
0
0
0
0
0
0
15
0
29
0
0
0
15
15
% P
% Gln:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
15
% Q
% Arg:
29
15
0
0
0
0
15
0
0
0
72
15
0
0
0
% R
% Ser:
0
0
0
0
72
15
0
0
29
15
0
58
15
58
0
% S
% Thr:
0
0
15
0
0
0
58
58
0
58
15
0
0
15
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _