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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAAH All Species: 17.58
Human Site: S126 Identified Species: 42.96
UniProt: O00519 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00519 NP_001432.2 579 63066 S126 A D C E T Q L S Q A P R Q G L
Chimpanzee Pan troglodytes XP_001161208 579 63035 S126 A D C E T Q L S Q A P R Q G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539627 579 62751 S126 A D C E T Q L S Q A P R R G L
Cat Felis silvestris
Mouse Mus musculus O08914 579 63203 S126 T D C E T Q L S Q A P R Q G L
Rat Rattus norvegicus P97612 579 63338 S126 T D C E T Q L S Q A P R Q G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90578 464 50873 A49 I Q Q K M E E A R R A R D L A
Frog Xenopus laevis NP_001091200 583 64351 K130 E A Q L Q E V K K Q K E K G L
Zebra Danio Brachydanio rerio NP_001103295 590 65073 M134 S V A Q L K D M N T Q K K G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501368 572 63982 L123 E L D E Q A K L P Y Y V K P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22580 549 61392 A110 F S E A L R L A D Y Y D S N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88.4 N.A. 83.9 82.7 N.A. N.A. 41.6 48.8 50.1 N.A. N.A. N.A. 38.1 N.A.
Protein Similarity: 100 99.8 N.A. 94.8 N.A. 92.2 91.3 N.A. N.A. 55.4 66.5 66.2 N.A. N.A. N.A. 56.2 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 6.6 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 33.3 40 46.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 10 10 0 10 0 20 0 50 10 0 0 0 10 % A
% Cys: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 10 0 0 0 10 0 10 0 0 10 10 0 0 % D
% Glu: 20 0 10 60 0 20 10 0 0 0 0 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 10 10 10 10 0 10 10 30 0 0 % K
% Leu: 0 10 0 10 20 0 60 10 0 0 0 0 0 10 70 % L
% Met: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 50 0 0 10 10 % P
% Gln: 0 10 20 10 20 50 0 0 50 10 10 0 40 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 10 0 60 10 0 10 % R
% Ser: 10 10 0 0 0 0 0 50 0 0 0 0 10 0 0 % S
% Thr: 20 0 0 0 50 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 20 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _