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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAAH All Species: 27.88
Human Site: T308 Identified Species: 68.15
UniProt: O00519 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00519 NP_001432.2 579 63066 T308 D M F R L D P T V P P L P F R
Chimpanzee Pan troglodytes XP_001161208 579 63035 T308 D M F R L D P T V P P L P F R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539627 579 62751 T308 D M F R L D P T V P P L P F K
Cat Felis silvestris
Mouse Mus musculus O08914 579 63203 T308 D L F R L D S T I P P L P F R
Rat Rattus norvegicus P97612 579 63338 T308 H L F T L D P T V P P L P F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90578 464 50873 S225 H Q K T P G G S S G G E G A L
Frog Xenopus laevis NP_001091200 583 64351 T312 D M F Q L D P T V P P V P F R
Zebra Danio Brachydanio rerio NP_001103295 590 65073 T316 D M F S L D P T I P P L P F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501368 572 63982 Y307 F Q S D R D P Y C P P V H W N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22580 549 61392 I303 W V Q D V K C I P Y H F D S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88.4 N.A. 83.9 82.7 N.A. N.A. 41.6 48.8 50.1 N.A. N.A. N.A. 38.1 N.A.
Protein Similarity: 100 99.8 N.A. 94.8 N.A. 92.2 91.3 N.A. N.A. 55.4 66.5 66.2 N.A. N.A. N.A. 56.2 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 80 N.A. N.A. 0 86.6 80 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 86.6 N.A. N.A. 6.6 100 86.6 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % C
% Asp: 60 0 0 20 0 80 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 0 70 0 0 0 0 0 0 0 0 10 0 70 0 % F
% Gly: 0 0 0 0 0 10 10 0 0 10 10 0 10 0 0 % G
% His: 20 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 20 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 20 0 0 70 0 0 0 0 0 0 60 0 0 10 % L
% Met: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 0 0 0 0 10 0 70 0 10 80 80 0 70 0 0 % P
% Gln: 0 20 10 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 40 10 0 0 0 0 0 0 0 0 0 50 % R
% Ser: 0 0 10 10 0 0 10 10 10 0 0 0 0 10 10 % S
% Thr: 0 0 0 20 0 0 0 70 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 10 0 0 0 50 0 0 20 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _