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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAAH All Species: 17.58
Human Site: T99 Identified Species: 42.96
UniProt: O00519 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00519 NP_001432.2 579 63066 T99 A P E A V L F T Y V G K A W E
Chimpanzee Pan troglodytes XP_001161208 579 63035 T99 S P E A V L F T Y V G K A W E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539627 579 62751 T99 S P E A A L F T Y V G K A W E
Cat Felis silvestris
Mouse Mus musculus O08914 579 63203 T99 S P E A V L F T Y L G K A W E
Rat Rattus norvegicus P97612 579 63338 T99 S P E A V F F T Y L G K A W E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90578 464 50873 A22 A D P R V L S A L F C G S A M
Frog Xenopus laevis NP_001091200 583 64351 E103 S V L V A Y I E K A L E V N K
Zebra Danio Brachydanio rerio NP_001103295 590 65073 M107 D A V L Y A F M E K T L E V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501368 572 63982 A96 Y F H K A I L A H E K T N A V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22580 549 61392 A83 S C H E I T A A F C H R A A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88.4 N.A. 83.9 82.7 N.A. N.A. 41.6 48.8 50.1 N.A. N.A. N.A. 38.1 N.A.
Protein Similarity: 100 99.8 N.A. 94.8 N.A. 92.2 91.3 N.A. N.A. 55.4 66.5 66.2 N.A. N.A. N.A. 56.2 N.A.
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 86.6 80 N.A. N.A. 20 0 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 93.3 N.A. N.A. 26.6 20 6.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 50 30 10 10 30 0 10 0 0 60 30 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 10 10 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 50 10 0 0 0 10 10 10 0 10 10 0 50 % E
% Phe: 0 10 0 0 0 10 60 0 10 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 50 10 0 0 0 % G
% His: 0 0 20 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 10 10 50 0 0 10 % K
% Leu: 0 0 10 10 0 50 10 0 10 20 10 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 10 % N
% Pro: 0 50 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 60 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 10 0 50 0 0 10 10 0 0 0 % T
% Val: 0 10 10 10 50 0 0 0 0 30 0 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % W
% Tyr: 10 0 0 0 10 10 0 0 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _