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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAAH All Species: 26.36
Human Site: Y329 Identified Species: 64.44
UniProt: O00519 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00519 NP_001432.2 579 63066 Y329 S Q P L R V G Y Y E T D N Y T
Chimpanzee Pan troglodytes XP_001161208 579 63035 Y329 S Q P L R V G Y Y E T D N Y T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539627 579 62751 Y329 S R P L R V G Y Y E T D N Y T
Cat Felis silvestris
Mouse Mus musculus O08914 579 63203 Y329 S R P L R V G Y Y E T D N Y T
Rat Rattus norvegicus P97612 579 63338 Y329 S R P L R V G Y Y E T D N Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90578 464 50873 V246 L L G I G S D V A G S I R L P
Frog Xenopus laevis NP_001091200 583 64351 F333 S K P L T I G F Y D T D G Y F
Zebra Danio Brachydanio rerio NP_001103295 590 65073 Y337 S K P L R I G Y Y E T D G Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501368 572 63982 Y328 E K K L R V G Y Y I D D G W F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22580 549 61392 Y324 N Y V V G I W Y G D G V I D P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88.4 N.A. 83.9 82.7 N.A. N.A. 41.6 48.8 50.1 N.A. N.A. N.A. 38.1 N.A.
Protein Similarity: 100 99.8 N.A. 94.8 N.A. 92.2 91.3 N.A. N.A. 55.4 66.5 66.2 N.A. N.A. N.A. 56.2 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 0 53.3 73.3 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 13.3 80 86.6 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 20 10 80 0 10 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 60 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 20 % F
% Gly: 0 0 10 0 20 0 80 0 10 10 10 0 30 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 30 0 0 0 10 0 10 10 0 0 % I
% Lys: 0 30 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 80 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % N
% Pro: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 20 % P
% Gln: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 30 0 0 70 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 70 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 70 0 0 0 50 % T
% Val: 0 0 10 10 0 60 0 10 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 0 0 0 80 80 0 0 0 0 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _