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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAAH
All Species:
24.24
Human Site:
Y454
Identified Species:
59.26
UniProt:
O00519
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00519
NP_001432.2
579
63066
Y454
L
Q
H
E
I
E
V
Y
R
K
T
V
I
A
Q
Chimpanzee
Pan troglodytes
XP_001161208
579
63035
Y454
L
Q
H
E
I
E
V
Y
R
K
T
V
I
A
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539627
579
62751
Y454
L
Q
H
E
I
E
V
Y
R
N
S
V
I
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
O08914
579
63203
Y454
L
Q
H
E
I
E
M
Y
R
Q
S
V
I
A
Q
Rat
Rattus norvegicus
P97612
579
63338
Y454
L
Q
H
E
I
E
M
Y
R
Q
S
V
I
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90578
464
50873
R358
K
R
A
V
Q
Q
T
R
K
L
L
Q
E
A
G
Frog
Xenopus laevis
NP_001091200
583
64351
Y459
H
N
A
A
I
K
E
Y
R
C
E
Y
I
N
E
Zebra Danio
Brachydanio rerio
NP_001103295
590
65073
Y463
Q
H
A
N
V
E
E
Y
I
Q
E
V
I
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501368
572
63982
Y451
A
Y
A
D
I
E
A
Y
R
E
E
F
V
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22580
549
61392
E438
D
Y
Y
L
S
F
P
E
S
E
R
P
D
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
88.4
N.A.
83.9
82.7
N.A.
N.A.
41.6
48.8
50.1
N.A.
N.A.
N.A.
38.1
N.A.
Protein Similarity:
100
99.8
N.A.
94.8
N.A.
92.2
91.3
N.A.
N.A.
55.4
66.5
66.2
N.A.
N.A.
N.A.
56.2
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
N.A.
6.6
26.6
33.3
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
26.6
40
53.3
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
40
10
0
0
10
0
0
0
0
0
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
50
0
70
20
10
0
20
30
0
10
0
20
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
10
10
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
70
0
0
0
10
0
0
0
70
0
10
% I
% Lys:
10
0
0
0
0
10
0
0
10
20
0
0
0
0
0
% K
% Leu:
50
0
0
10
0
0
0
0
0
10
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
10
50
0
0
10
10
0
0
0
30
0
10
0
0
50
% Q
% Arg:
0
10
0
0
0
0
0
10
70
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
0
30
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% T
% Val:
0
0
0
10
10
0
30
0
0
0
0
60
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
10
0
0
0
0
80
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _