KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAAH
All Species:
24.55
Human Site:
Y523
Identified Species:
60
UniProt:
O00519
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00519
NP_001432.2
579
63066
Y523
D
E
A
Q
M
E
H
Y
R
G
Y
F
G
D
I
Chimpanzee
Pan troglodytes
XP_001161208
579
63035
Y523
D
E
A
Q
M
E
H
Y
R
G
Y
F
G
D
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539627
579
62751
Y523
D
E
A
Q
M
E
H
Y
K
G
Y
Y
G
D
I
Cat
Felis silvestris
Mouse
Mus musculus
O08914
579
63203
Y523
D
D
A
Q
M
E
H
Y
K
G
Y
F
G
D
M
Rat
Rattus norvegicus
P97612
579
63338
Y523
D
D
A
Q
M
E
L
Y
K
G
Y
F
G
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90578
464
50873
L426
P
A
L
V
K
R
I
L
A
I
I
L
K
P
I
Frog
Xenopus laevis
NP_001091200
583
64351
Y528
D
E
E
E
L
K
N
Y
K
G
Y
Y
N
D
L
Zebra Danio
Brachydanio rerio
NP_001103295
590
65073
Y532
D
E
A
Q
L
R
Q
Y
T
G
A
H
G
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501368
572
63982
E521
D
E
E
K
L
I
N
E
Y
P
E
T
D
K
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22580
549
61392
I506
L
N
P
E
D
K
M
I
K
T
Y
W
N
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
88.4
N.A.
83.9
82.7
N.A.
N.A.
41.6
48.8
50.1
N.A.
N.A.
N.A.
38.1
N.A.
Protein Similarity:
100
99.8
N.A.
94.8
N.A.
92.2
91.3
N.A.
N.A.
55.4
66.5
66.2
N.A.
N.A.
N.A.
56.2
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
N.A.
6.6
40
53.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
6.6
86.6
60
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
60
0
0
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
20
0
0
10
0
0
0
0
0
0
0
10
80
0
% D
% Glu:
0
60
20
20
0
50
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
70
0
0
60
0
0
% G
% His:
0
0
0
0
0
0
40
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
0
10
10
0
0
0
50
% I
% Lys:
0
0
0
10
10
20
0
0
50
0
0
0
10
10
0
% K
% Leu:
10
0
10
0
30
0
10
10
0
0
0
10
0
0
20
% L
% Met:
0
0
0
0
50
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
20
0
0
0
0
0
20
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
0
10
0
0
0
10
10
% P
% Gln:
0
0
0
60
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
70
10
0
70
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _