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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRIT1
All Species:
28.79
Human Site:
S583
Identified Species:
70.37
UniProt:
O00522
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00522
NP_004903.2
736
84348
S583
L
N
E
E
N
L
K
S
I
V
P
V
T
K
L
Chimpanzee
Pan troglodytes
XP_001165880
736
84342
S583
L
N
E
E
N
L
K
S
I
V
P
V
T
K
L
Rhesus Macaque
Macaca mulatta
XP_001101416
736
84321
S583
L
N
E
E
N
L
K
S
I
V
P
V
T
K
L
Dog
Lupus familis
XP_539416
736
84378
S583
L
N
E
E
N
L
K
S
I
V
P
I
T
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6S5J6
736
83963
S583
L
N
E
E
T
L
K
S
I
V
P
I
T
K
L
Rat
Rattus norvegicus
NP_001102088
736
83987
S583
L
N
E
E
N
L
K
S
I
V
P
I
T
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521606
418
46918
M275
Q
E
K
W
R
R
S
M
S
S
V
M
E
D
K
Chicken
Gallus gallus
NP_001026144
737
84255
S584
L
N
E
E
N
L
K
S
I
V
P
I
T
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665643
659
75764
T514
K
S
K
A
H
H
W
T
N
R
I
L
H
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797833
532
60450
V389
I
V
N
E
H
R
N
V
T
Q
K
G
I
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.3
98.9
N.A.
94.5
95.2
N.A.
51.2
91.5
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
99.8
99.3
99.7
N.A.
96.4
96.7
N.A.
54
95.7
N.A.
77.1
N.A.
N.A.
N.A.
N.A.
46.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
0
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
100
N.A.
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
10
70
80
0
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
20
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
70
0
10
40
10
0
0
% I
% Lys:
10
0
20
0
0
0
70
0
0
0
10
0
0
70
10
% K
% Leu:
70
0
0
0
0
70
0
0
0
0
0
10
0
0
70
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
70
10
0
60
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
20
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
10
70
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
10
10
0
0
0
70
0
0
% T
% Val:
0
10
0
0
0
0
0
10
0
70
10
30
0
0
0
% V
% Trp:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _