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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHL1
All Species:
18.18
Human Site:
S1137
Identified Species:
36.36
UniProt:
O00533
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00533
NP_006605.2
1208
135057
S1137
D
E
T
F
G
E
Y
S
D
S
D
E
K
P
L
Chimpanzee
Pan troglodytes
XP_001136570
1209
135175
S1138
D
E
T
F
G
E
Y
S
D
S
D
E
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001097680
1199
133742
S1128
D
E
T
F
G
E
Y
S
D
S
D
E
K
P
L
Dog
Lupus familis
XP_533760
1245
139039
S1174
D
E
T
F
G
E
Y
S
D
S
D
E
K
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P70232
1209
134911
S1138
D
E
T
F
G
E
Y
S
D
S
D
E
K
P
L
Rat
Rattus norvegicus
P97686
1214
133893
E1134
E
D
D
G
T
F
G
E
Y
S
D
A
E
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505304
1155
129323
G1085
E
D
V
I
E
T
K
G
R
V
Y
A
G
I
Y
Chicken
Gallus gallus
P35331
1284
141833
E1200
E
D
D
G
T
F
G
E
Y
R
S
L
E
S
D
Frog
Xenopus laevis
NP_001085487
1177
130907
E1097
E
D
D
G
T
F
G
E
Y
S
D
A
E
D
H
Zebra Danio
Brachydanio rerio
Q90478
1197
132843
R1109
D
D
A
F
G
E
Y
R
S
L
E
S
D
M
E
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
R1190
D
E
T
F
G
E
Y
R
S
L
E
S
D
L
E
Fruit Fly
Dros. melanogaster
P20241
1302
143599
P1188
G
F
H
E
Y
S
Q
P
L
D
N
K
S
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.5
88.2
N.A.
83.8
40.6
N.A.
60
40.6
40.4
35
35.2
28.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
96.5
92.6
N.A.
91
57
N.A.
72.2
56.7
57
52.9
52
45
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
0
0
13.3
33.3
46.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
13.3
20
33.3
46.6
53.3
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
25
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
42
25
0
0
0
0
0
42
9
59
0
17
17
9
% D
% Glu:
34
50
0
9
9
59
0
25
0
0
17
42
25
0
17
% E
% Phe:
0
9
0
59
0
25
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
25
59
0
25
9
0
0
0
0
9
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
9
42
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
17
0
9
0
9
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
42
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
9
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
42
17
59
9
17
9
9
0
% S
% Thr:
0
0
50
0
25
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
59
0
25
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _