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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHL1 All Species: 18.18
Human Site: S1199 Identified Species: 36.36
UniProt: O00533 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00533 NP_006605.2 1208 135057 S1199 G S V E S N G S S T A T F P L
Chimpanzee Pan troglodytes XP_001136570 1209 135175 S1200 G S V E S N G S S T A T F P L
Rhesus Macaque Macaca mulatta XP_001097680 1199 133742 S1190 G S V E S N G S S T A T F P L
Dog Lupus familis XP_533760 1245 139039 S1236 G S V E S N G S S T A T F P L
Cat Felis silvestris
Mouse Mus musculus P70232 1209 134911 S1200 G S V E S N G S S T A T F P L
Rat Rattus norvegicus P97686 1214 133893 E1196 K K E K E P A E G N E S S E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505304 1155 129323 K1147 D P E V Q S I K D E T F G E Y
Chicken Gallus gallus P35331 1284 141833 K1262 Q Y S G K K E K E P A E G N E
Frog Xenopus laevis NP_001085487 1177 130907 E1159 K K E K E P V E G N E S S E A
Zebra Danio Brachydanio rerio Q90478 1197 132843 A1171 R G H D S S G A V S P V N P N
Tiger Blowfish Takifugu rubipres Q98902 1277 141937 H1252 S E G P E P F H G V P D N S P
Fruit Fly Dros. melanogaster P20241 1302 143599 N1250 P V S P Q P L N N S A A A H Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.5 88.2 N.A. 83.8 40.6 N.A. 60 40.6 40.4 35 35.2 28.5 N.A. N.A. N.A.
Protein Similarity: 100 99.5 96.5 92.6 N.A. 91 57 N.A. 72.2 56.7 57 52.9 52 45 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 0 6.6 0 20 0 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 6.6 13.3 46.6 0 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 0 0 59 9 9 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 0 0 0 9 0 0 9 0 0 0 % D
% Glu: 0 9 25 42 25 0 9 17 9 9 17 9 0 25 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 9 42 0 0 % F
% Gly: 42 9 9 9 0 0 50 0 25 0 0 0 17 0 0 % G
% His: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 17 17 0 17 9 9 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 42 0 9 9 17 0 0 17 9 9 % N
% Pro: 9 9 0 17 0 34 0 0 0 9 17 0 0 50 9 % P
% Gln: 9 0 0 0 17 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 42 17 0 50 17 0 42 42 17 0 17 17 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 42 9 42 0 0 0 % T
% Val: 0 9 42 9 0 0 9 0 9 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _