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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PES1
All Species:
21.82
Human Site:
S530
Identified Species:
34.29
UniProt:
O00541
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00541
NP_055118.1
588
68003
S530
R
L
A
Q
E
E
E
S
E
A
K
R
L
A
I
Chimpanzee
Pan troglodytes
XP_001143647
588
67990
S530
R
L
A
Q
E
E
E
S
E
A
K
R
L
A
I
Rhesus Macaque
Macaca mulatta
XP_001110399
679
77752
S621
R
L
A
Q
E
E
E
S
E
A
K
R
L
A
I
Dog
Lupus familis
XP_543480
584
67748
N526
R
L
A
Q
E
E
E
N
E
A
K
R
L
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ61
584
67777
S526
R
L
A
Q
E
E
E
S
E
A
K
R
L
A
I
Rat
Rattus norvegicus
Q3B8N8
586
67586
S528
R
L
A
Q
E
E
E
S
E
A
K
R
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508188
378
43758
K339
R
E
K
Y
L
Y
R
K
I
M
F
G
K
R
R
Chicken
Gallus gallus
XP_001234133
524
60851
Y481
M
M
K
K
R
E
K
Y
L
Y
K
K
I
M
F
Frog
Xenopus laevis
Q7ZY69
574
67098
N517
Q
V
A
E
Q
E
K
N
E
E
K
R
L
A
I
Zebra Danio
Brachydanio rerio
P79741
583
67880
A526
R
A
A
E
E
E
K
A
E
E
K
R
L
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL96
627
73844
D555
Q
V
H
K
A
E
V
D
E
H
R
L
Q
A
R
Honey Bee
Apis mellifera
XP_001119862
555
66223
K504
L
R
E
R
M
I
K
K
K
H
R
N
L
Y
R
Nematode Worm
Caenorhab. elegans
Q95Y89
531
61607
T480
S
K
E
K
F
H
E
T
V
E
K
G
Q
E
L
Sea Urchin
Strong. purpuratus
XP_001200338
596
69851
R538
W
D
A
E
K
L
A
R
Q
E
R
R
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SFC2
663
75275
A609
R
K
A
L
E
K
K
A
R
E
E
A
E
D
L
Conservation
Percent
Protein Identity:
100
99.3
83
90.3
N.A.
89.4
89.4
N.A.
47.4
72.6
71.4
73.9
N.A.
43.2
46
42.6
49.6
Protein Similarity:
100
99.4
85.1
94.3
N.A.
93.8
94
N.A.
55.6
80.2
86.2
84
N.A.
60.7
62.5
58.5
66.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
13.3
53.3
66.6
N.A.
20
6.6
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
46.6
93.3
86.6
N.A.
46.6
33.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
67
0
7
0
7
14
0
40
0
7
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
0
0
0
0
0
7
0
% D
% Glu:
0
7
14
20
54
67
47
0
60
34
7
0
7
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% G
% His:
0
0
7
0
0
7
0
0
0
14
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
54
% I
% Lys:
0
14
14
20
7
7
34
14
7
0
67
7
7
0
0
% K
% Leu:
7
40
0
7
7
7
0
0
7
0
0
7
67
0
14
% L
% Met:
7
7
0
0
7
0
0
0
0
7
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
40
7
0
0
0
7
0
0
0
14
7
0
% Q
% Arg:
60
7
0
7
7
0
7
7
7
0
20
60
0
7
20
% R
% Ser:
7
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
14
0
0
0
0
7
0
7
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
0
7
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _