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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PES1
All Species:
26.36
Human Site:
T385
Identified Species:
41.43
UniProt:
O00541
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00541
NP_055118.1
588
68003
T385
V
D
R
P
G
Q
Q
T
S
V
I
G
R
C
Y
Chimpanzee
Pan troglodytes
XP_001143647
588
67990
T385
V
D
R
P
G
Q
Q
T
S
V
I
G
R
C
Y
Rhesus Macaque
Macaca mulatta
XP_001110399
679
77752
T476
V
D
R
P
G
Q
Q
T
S
V
I
G
R
C
Y
Dog
Lupus familis
XP_543480
584
67748
T384
V
D
R
P
G
Q
Q
T
P
V
L
G
R
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ61
584
67777
T384
V
D
R
P
G
Q
Q
T
P
I
I
G
R
Y
Y
Rat
Rattus norvegicus
Q3B8N8
586
67586
T384
V
D
R
P
G
Q
Q
T
P
I
I
G
R
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508188
378
43758
L230
D
Y
V
P
P
E
K
L
K
L
L
A
L
Q
R
Chicken
Gallus gallus
XP_001234133
524
60851
Q372
V
D
R
P
R
V
E
Q
Q
V
V
G
R
Y
Y
Frog
Xenopus laevis
Q7ZY69
574
67098
T386
V
D
R
P
S
I
Q
T
Q
I
I
N
R
Y
Y
Zebra Danio
Brachydanio rerio
P79741
583
67880
K386
V
D
R
P
S
M
D
K
Q
Y
I
N
R
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL96
627
73844
T384
V
D
R
P
S
I
T
T
Q
Y
I
S
R
D
Y
Honey Bee
Apis mellifera
XP_001119862
555
66223
K384
V
D
R
P
N
M
S
K
Q
Y
I
S
R
Y
Y
Nematode Worm
Caenorhab. elegans
Q95Y89
531
61607
K368
V
V
D
R
P
M
D
K
L
E
V
N
R
L
Y
Sea Urchin
Strong. purpuratus
XP_001200338
596
69851
K387
V
D
R
P
Q
Q
D
K
Q
Y
L
S
R
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SFC2
663
75275
Q447
A
Q
K
V
G
P
N
Q
R
Y
P
G
R
I
Y
Conservation
Percent
Protein Identity:
100
99.3
83
90.3
N.A.
89.4
89.4
N.A.
47.4
72.6
71.4
73.9
N.A.
43.2
46
42.6
49.6
Protein Similarity:
100
99.4
85.1
94.3
N.A.
93.8
94
N.A.
55.6
80.2
86.2
84
N.A.
60.7
62.5
58.5
66.6
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
6.6
53.3
60
46.6
N.A.
53.3
46.6
20
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
33.3
66.6
66.6
46.6
N.A.
53.3
46.6
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% C
% Asp:
7
80
7
0
0
0
20
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
7
7
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
47
0
0
0
0
0
0
54
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
0
0
0
20
60
0
0
7
0
% I
% Lys:
0
0
7
0
0
0
7
27
7
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
7
7
7
20
0
7
7
0
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
20
0
0
0
% N
% Pro:
0
0
0
87
14
7
0
0
20
0
7
0
0
0
0
% P
% Gln:
0
7
0
0
7
47
47
14
40
0
0
0
0
7
0
% Q
% Arg:
0
0
80
7
7
0
0
0
7
0
0
0
94
0
7
% R
% Ser:
0
0
0
0
20
0
7
0
20
0
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
54
0
0
0
0
0
0
0
% T
% Val:
87
7
7
7
0
7
0
0
0
34
14
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
34
0
0
0
54
94
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _