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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PES1
All Species:
43.33
Human Site:
Y65
Identified Species:
68.1
UniProt:
O00541
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00541
NP_055118.1
588
68003
Y65
S
T
A
A
R
T
F
Y
L
I
K
D
I
R
F
Chimpanzee
Pan troglodytes
XP_001143647
588
67990
Y65
S
T
A
A
R
T
F
Y
L
I
K
D
I
R
F
Rhesus Macaque
Macaca mulatta
XP_001110399
679
77752
Y156
S
T
A
A
R
T
F
Y
L
I
K
D
I
R
F
Dog
Lupus familis
XP_543480
584
67748
Y65
S
T
A
A
R
T
F
Y
L
L
K
D
I
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ61
584
67777
Y65
S
T
A
A
R
T
F
Y
L
I
K
D
I
K
F
Rat
Rattus norvegicus
Q3B8N8
586
67586
Y65
S
T
A
A
R
T
F
Y
L
I
K
D
I
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508188
378
43758
Chicken
Gallus gallus
XP_001234133
524
60851
K62
A
R
T
F
Y
L
L
K
D
I
K
F
L
L
H
Frog
Xenopus laevis
Q7ZY69
574
67098
Y65
S
T
A
P
R
T
F
Y
L
L
K
D
I
K
F
Zebra Danio
Brachydanio rerio
P79741
583
67880
Y65
S
T
A
A
R
T
Y
Y
L
L
K
D
I
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL96
627
73844
Y63
S
S
E
I
K
V
L
Y
H
T
K
D
I
R
F
Honey Bee
Apis mellifera
XP_001119862
555
66223
Y65
D
P
S
I
K
I
L
Y
H
K
K
D
I
Q
F
Nematode Worm
Caenorhab. elegans
Q95Y89
531
61607
Y65
S
T
A
N
K
V
F
Y
Y
R
K
D
I
N
F
Sea Urchin
Strong. purpuratus
XP_001200338
596
69851
F64
Q
R
L
H
R
T
Y
F
R
F
K
D
I
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SFC2
663
75275
Y64
A
T
A
S
T
T
F
Y
Y
T
K
D
I
Q
Y
Conservation
Percent
Protein Identity:
100
99.3
83
90.3
N.A.
89.4
89.4
N.A.
47.4
72.6
71.4
73.9
N.A.
43.2
46
42.6
49.6
Protein Similarity:
100
99.4
85.1
94.3
N.A.
93.8
94
N.A.
55.6
80.2
86.2
84
N.A.
60.7
62.5
58.5
66.6
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
0
13.3
80
86.6
N.A.
46.6
33.3
60
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
26.6
93.3
100
N.A.
60
53.3
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
67
47
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
0
0
87
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
60
7
0
7
0
7
0
0
80
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
14
0
0
0
0
0
7
% H
% Ile:
0
0
0
14
0
7
0
0
0
40
0
0
87
0
0
% I
% Lys:
0
0
0
0
20
0
0
7
0
7
94
0
0
27
0
% K
% Leu:
0
0
7
0
0
7
20
0
54
20
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
14
0
0
60
0
0
0
7
7
0
0
0
34
0
% R
% Ser:
67
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
67
7
0
7
67
0
0
0
14
0
0
0
0
0
% T
% Val:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
14
80
14
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _