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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLL1 All Species: 7.27
Human Site: S626 Identified Species: 13.33
UniProt: O00548 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00548 NP_005609.3 723 78056 S626 A D F H G D H S A D K N G F K
Chimpanzee Pan troglodytes XP_510318 685 74575 T588 P A A Q L K N T N Q K K E L E
Rhesus Macaque Macaca mulatta XP_001099250 685 74578 T588 P A A Q L K N T N Q K K E L E
Dog Lupus familis XP_849154 685 74341 T588 P A A Q L K N T N Q K K E L E
Cat Felis silvestris
Mouse Mus musculus Q61483 722 78430 G626 A D F H G D H G A K K S S F K
Rat Rattus norvegicus P97677 714 77360 G618 A D F H G D H G A D K S S F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518138 509 54239 Y413 P N G F K A R Y P A V D Y N L
Chicken Gallus gallus NP_990304 728 79843 S631 N K K V D F H S D N S D K N G
Frog Xenopus laevis NP_001079551 642 70637 G545 V M R G M R R G H F N E K G R
Zebra Danio Brachydanio rerio Q8UWJ4 717 79043 V620 V K N I N K K V D F Q S D G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10041 833 88822 N724 V A S V A D N N N A N S D F C
Honey Bee Apis mellifera XP_393831 1119 119736 T986 S S F Q T D V T L D S S C S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 N950 G M W Y N E C N D Q V T I T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.9 51 51 N.A. 88.5 88.5 N.A. 56.5 83.6 48.9 70.4 N.A. 37.3 31.8 N.A. 23.9
Protein Similarity: 100 64.5 64.3 63.4 N.A. 94.4 93.6 N.A. 60.5 90.1 62.5 82.5 N.A. 50.1 41 N.A. 34.9
P-Site Identity: 100 6.6 6.6 6.6 N.A. 73.3 80 N.A. 0 13.3 0 0 N.A. 13.3 20 N.A. 6.6
P-Site Similarity: 100 26.6 26.6 26.6 N.A. 80 86.6 N.A. 13.3 26.6 6.6 13.3 N.A. 33.3 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 31 24 0 8 8 0 0 24 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % C
% Asp: 0 24 0 0 8 39 0 0 24 24 0 16 16 0 8 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 8 24 0 24 % E
% Phe: 0 0 31 8 0 8 0 0 0 16 0 0 0 31 0 % F
% Gly: 8 0 8 8 24 0 0 24 0 0 0 0 8 16 16 % G
% His: 0 0 0 24 0 0 31 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 16 8 0 8 31 8 0 0 8 47 24 16 0 31 % K
% Leu: 0 0 0 0 24 0 0 0 8 0 0 0 0 24 8 % L
% Met: 0 16 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 8 0 16 0 31 16 31 8 16 8 0 16 0 % N
% Pro: 31 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 31 0 0 0 0 0 31 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 8 16 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 8 0 0 0 0 16 0 0 16 39 16 8 0 % S
% Thr: 0 0 0 0 8 0 0 31 0 0 0 8 0 8 0 % T
% Val: 24 0 0 16 0 0 8 8 0 0 16 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _