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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLL1
All Species:
9.09
Human Site:
T587
Identified Species:
16.67
UniProt:
O00548
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00548
NP_005609.3
723
78056
T587
A
D
P
C
R
G
E
T
E
T
M
N
N
L
A
Chimpanzee
Pan troglodytes
XP_510318
685
74575
A549
L
V
L
L
G
M
V
A
V
A
V
R
Q
L
R
Rhesus Macaque
Macaca mulatta
XP_001099250
685
74578
A549
L
V
L
L
G
M
V
A
V
A
V
R
Q
L
R
Dog
Lupus familis
XP_849154
685
74341
A549
L
V
L
L
G
M
V
A
V
A
V
R
Q
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61483
722
78430
T587
P
E
P
C
G
G
E
T
E
T
M
N
N
L
A
Rat
Rattus norvegicus
P97677
714
77360
T579
P
D
P
C
G
G
E
T
E
T
M
N
N
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518138
509
54239
Q374
M
N
N
L
A
N
C
Q
R
E
K
D
I
S
V
Chicken
Gallus gallus
NP_990304
728
79843
R592
H
H
Q
P
E
A
C
R
S
E
T
E
T
M
N
Frog
Xenopus laevis
NP_001079551
642
70637
P506
F
R
V
H
D
P
T
P
A
S
H
R
A
D
S
Zebra Danio
Brachydanio rerio
Q8UWJ4
717
79043
I581
L
Q
Q
R
S
Q
Q
I
D
S
H
S
E
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
T685
N
P
N
I
I
K
N
T
W
D
K
S
V
N
N
Honey Bee
Apis mellifera
XP_393831
1119
119736
T947
G
G
G
G
S
V
C
T
L
G
T
G
D
A
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
G911
S
L
P
C
Q
N
G
G
L
C
I
D
G
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.9
51
51
N.A.
88.5
88.5
N.A.
56.5
83.6
48.9
70.4
N.A.
37.3
31.8
N.A.
23.9
Protein Similarity:
100
64.5
64.3
63.4
N.A.
94.4
93.6
N.A.
60.5
90.1
62.5
82.5
N.A.
50.1
41
N.A.
34.9
P-Site Identity:
100
6.6
6.6
6.6
N.A.
80
86.6
N.A.
0
0
0
0
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
86.6
86.6
N.A.
13.3
6.6
13.3
33.3
N.A.
13.3
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
24
8
24
0
0
8
8
31
% A
% Cys:
0
0
0
31
0
0
24
0
0
8
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
0
0
0
8
8
0
16
8
8
0
% D
% Glu:
0
8
0
0
8
0
24
0
24
16
0
8
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
8
39
24
8
8
0
8
0
8
8
0
0
% G
% His:
8
8
0
8
0
0
0
0
0
0
16
0
0
0
8
% H
% Ile:
0
0
0
8
8
0
0
8
0
0
8
0
8
16
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% K
% Leu:
31
8
24
31
0
0
0
0
16
0
0
0
0
47
0
% L
% Met:
8
0
0
0
0
24
0
0
0
0
24
0
0
8
0
% M
% Asn:
8
8
16
0
0
16
8
0
0
0
0
24
24
8
16
% N
% Pro:
16
8
31
8
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
16
0
8
8
8
8
0
0
0
0
24
0
0
% Q
% Arg:
0
8
0
8
8
0
0
8
8
0
0
31
0
0
24
% R
% Ser:
8
0
0
0
16
0
0
0
8
16
0
16
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
39
0
24
16
0
8
0
0
% T
% Val:
0
24
8
0
0
8
24
0
24
0
24
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _