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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLL1 All Species: 9.09
Human Site: T587 Identified Species: 16.67
UniProt: O00548 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00548 NP_005609.3 723 78056 T587 A D P C R G E T E T M N N L A
Chimpanzee Pan troglodytes XP_510318 685 74575 A549 L V L L G M V A V A V R Q L R
Rhesus Macaque Macaca mulatta XP_001099250 685 74578 A549 L V L L G M V A V A V R Q L R
Dog Lupus familis XP_849154 685 74341 A549 L V L L G M V A V A V R Q L R
Cat Felis silvestris
Mouse Mus musculus Q61483 722 78430 T587 P E P C G G E T E T M N N L A
Rat Rattus norvegicus P97677 714 77360 T579 P D P C G G E T E T M N N L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518138 509 54239 Q374 M N N L A N C Q R E K D I S V
Chicken Gallus gallus NP_990304 728 79843 R592 H H Q P E A C R S E T E T M N
Frog Xenopus laevis NP_001079551 642 70637 P506 F R V H D P T P A S H R A D S
Zebra Danio Brachydanio rerio Q8UWJ4 717 79043 I581 L Q Q R S Q Q I D S H S E I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10041 833 88822 T685 N P N I I K N T W D K S V N N
Honey Bee Apis mellifera XP_393831 1119 119736 T947 G G G G S V C T L G T G D A H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 G911 S L P C Q N G G L C I D G I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.9 51 51 N.A. 88.5 88.5 N.A. 56.5 83.6 48.9 70.4 N.A. 37.3 31.8 N.A. 23.9
Protein Similarity: 100 64.5 64.3 63.4 N.A. 94.4 93.6 N.A. 60.5 90.1 62.5 82.5 N.A. 50.1 41 N.A. 34.9
P-Site Identity: 100 6.6 6.6 6.6 N.A. 80 86.6 N.A. 0 0 0 0 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 13.3 13.3 13.3 N.A. 86.6 86.6 N.A. 13.3 6.6 13.3 33.3 N.A. 13.3 13.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 8 0 24 8 24 0 0 8 8 31 % A
% Cys: 0 0 0 31 0 0 24 0 0 8 0 0 0 0 0 % C
% Asp: 0 16 0 0 8 0 0 0 8 8 0 16 8 8 0 % D
% Glu: 0 8 0 0 8 0 24 0 24 16 0 8 8 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 8 39 24 8 8 0 8 0 8 8 0 0 % G
% His: 8 8 0 8 0 0 0 0 0 0 16 0 0 0 8 % H
% Ile: 0 0 0 8 8 0 0 8 0 0 8 0 8 16 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 16 0 0 0 0 % K
% Leu: 31 8 24 31 0 0 0 0 16 0 0 0 0 47 0 % L
% Met: 8 0 0 0 0 24 0 0 0 0 24 0 0 8 0 % M
% Asn: 8 8 16 0 0 16 8 0 0 0 0 24 24 8 16 % N
% Pro: 16 8 31 8 0 8 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 8 16 0 8 8 8 8 0 0 0 0 24 0 0 % Q
% Arg: 0 8 0 8 8 0 0 8 8 0 0 31 0 0 24 % R
% Ser: 8 0 0 0 16 0 0 0 8 16 0 16 0 8 8 % S
% Thr: 0 0 0 0 0 0 8 39 0 24 16 0 8 0 0 % T
% Val: 0 24 8 0 0 8 24 0 24 0 24 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _