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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLL1
All Species:
9.39
Human Site:
T663
Identified Species:
17.22
UniProt:
O00548
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00548
NP_005609.3
723
78056
T663
D
A
H
S
K
R
D
T
K
C
Q
P
Q
G
S
Chimpanzee
Pan troglodytes
XP_510318
685
74575
G625
A
P
G
P
L
G
R
G
T
M
P
G
K
F
P
Rhesus Macaque
Macaca mulatta
XP_001099250
685
74578
G625
A
P
G
P
L
G
R
G
T
M
P
G
K
F
P
Dog
Lupus familis
XP_849154
685
74341
G625
A
P
G
P
L
G
R
G
T
M
L
G
K
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61483
722
78430
T663
D
T
H
S
K
R
D
T
K
C
Q
S
Q
S
S
Rat
Rattus norvegicus
P97677
714
77360
T655
D
A
H
S
K
R
D
T
K
C
Q
S
Q
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518138
509
54239
L450
P
E
R
T
P
A
P
L
K
S
G
D
G
S
E
Chicken
Gallus gallus
NP_990304
728
79843
E668
K
E
E
H
G
K
C
E
A
K
C
E
T
Y
D
Frog
Xenopus laevis
NP_001079551
642
70637
S582
P
D
Y
L
R
E
K
S
S
S
K
Q
K
L
L
Zebra Danio
Brachydanio rerio
Q8UWJ4
717
79043
E657
D
L
G
K
E
D
S
E
R
S
E
A
T
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
A761
G
S
P
A
G
S
S
A
K
G
A
S
G
G
G
Honey Bee
Apis mellifera
XP_393831
1119
119736
L1023
A
A
H
R
A
S
H
L
F
Q
K
E
K
D
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
A987
P
T
V
V
V
G
Y
A
S
N
N
Y
D
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.9
51
51
N.A.
88.5
88.5
N.A.
56.5
83.6
48.9
70.4
N.A.
37.3
31.8
N.A.
23.9
Protein Similarity:
100
64.5
64.3
63.4
N.A.
94.4
93.6
N.A.
60.5
90.1
62.5
82.5
N.A.
50.1
41
N.A.
34.9
P-Site Identity:
100
0
0
6.6
N.A.
80
93.3
N.A.
6.6
0
0
6.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
6.6
6.6
13.3
N.A.
80
93.3
N.A.
13.3
6.6
33.3
26.6
N.A.
26.6
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
24
0
8
8
8
0
16
8
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
24
8
0
0
0
16
% C
% Asp:
31
8
0
0
0
8
24
0
0
0
0
8
8
8
8
% D
% Glu:
0
16
8
0
8
8
0
16
0
0
8
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
24
0
% F
% Gly:
8
0
31
0
16
31
0
24
0
8
8
24
16
24
8
% G
% His:
0
0
31
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
24
8
8
0
39
8
16
0
39
8
0
% K
% Leu:
0
8
0
8
24
0
0
16
0
0
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
24
24
8
24
8
0
8
0
0
0
16
8
0
0
24
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
24
8
24
0
0
% Q
% Arg:
0
0
8
8
8
24
24
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
24
0
16
16
8
16
24
0
24
0
16
31
% S
% Thr:
0
16
0
8
0
0
0
24
24
0
0
0
16
0
0
% T
% Val:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
8
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _