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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLL1 All Species: 11.21
Human Site: Y641 Identified Species: 20.56
UniProt: O00548 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00548 NP_005609.3 723 78056 Y641 A R Y P A V D Y N L V Q D L K
Chimpanzee Pan troglodytes XP_510318 685 74575 S603 V D C G L D K S N C G K Q Q N
Rhesus Macaque Macaca mulatta XP_001099250 685 74578 S603 V D C G L D K S N C G K Q Q N
Dog Lupus familis XP_849154 685 74341 S603 V D C G L D K S N C G K Q Q N
Cat Felis silvestris
Mouse Mus musculus Q61483 722 78430 Y641 V R Y P T V D Y N L V R D L K
Rat Rattus norvegicus P97677 714 77360 Y633 A R Y P T V D Y N L I R D L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518138 509 54239 E428 V P D L K S A E R G G E D L G
Chicken Gallus gallus NP_990304 728 79843 V646 Y K V R Y P S V D Y N L V H E
Frog Xenopus laevis NP_001079551 642 70637 K560 V N N D L E P K N N L I E K E
Zebra Danio Brachydanio rerio Q8UWJ4 717 79043 Y635 K N G F K S R Y S L V D Y N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10041 833 88822 K739 V A P L Q R A K S Q K Q L N T
Honey Bee Apis mellifera XP_393831 1119 119736 A1001 Y K P E P V L A D G R T R T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 G965 T S T G M M L G D Y M T Y N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.9 51 51 N.A. 88.5 88.5 N.A. 56.5 83.6 48.9 70.4 N.A. 37.3 31.8 N.A. 23.9
Protein Similarity: 100 64.5 64.3 63.4 N.A. 94.4 93.6 N.A. 60.5 90.1 62.5 82.5 N.A. 50.1 41 N.A. 34.9
P-Site Identity: 100 6.6 6.6 6.6 N.A. 80 80 N.A. 13.3 0 6.6 20 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 13.3 13.3 13.3 N.A. 86.6 93.3 N.A. 20 20 26.6 26.6 N.A. 13.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 0 8 0 16 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 24 0 0 0 0 0 0 24 0 0 0 0 0 % C
% Asp: 0 24 8 8 0 24 24 0 24 0 0 8 31 0 0 % D
% Glu: 0 0 0 8 0 8 0 8 0 0 0 8 8 0 24 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 31 0 0 0 8 0 16 31 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % I
% Lys: 8 16 0 0 16 0 24 16 0 0 8 24 0 8 24 % K
% Leu: 0 0 0 16 31 0 16 0 0 31 8 8 8 31 8 % L
% Met: 0 0 0 0 8 8 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 16 8 0 0 0 0 0 54 8 8 0 0 24 24 % N
% Pro: 0 8 16 24 8 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 0 16 24 24 0 % Q
% Arg: 0 24 0 8 0 8 8 0 8 0 8 16 8 0 0 % R
% Ser: 0 8 0 0 0 16 8 24 16 0 0 0 0 0 0 % S
% Thr: 8 0 8 0 16 0 0 0 0 0 0 16 0 8 16 % T
% Val: 54 0 8 0 0 31 0 8 0 0 24 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 24 0 8 0 0 31 0 16 0 0 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _