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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
3.64
Human Site:
S2247
Identified Species:
8
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S2247
R
A
R
D
Q
R
W
S
R
S
P
S
E
G
R
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2536
A
A
G
P
G
L
P
P
G
E
G
P
T
G
C
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2116
E
S
P
E
R
R
Q
S
R
S
P
S
E
G
R
Dog
Lupus familis
XP_537779
2046
229120
P1798
S
S
A
A
G
P
G
P
P
L
G
E
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
L2119
H
R
T
S
E
R
S
L
G
R
Y
T
D
V
D
Rat
Rattus norvegicus
P54282
2212
251509
D1964
A
L
P
S
T
Q
L
D
P
G
G
G
L
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
P1942
P
R
R
R
L
L
P
P
T
P
A
S
N
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
D2052
R
S
L
S
R
Y
T
D
A
D
T
G
L
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
G1603
S
H
P
R
Y
P
R
G
S
W
S
A
S
T
S
Honey Bee
Apis mellifera
NP_001159376
1904
215872
K1656
E
S
L
T
H
T
G
K
R
L
H
P
P
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
D1718
R
A
P
I
S
T
R
D
V
S
P
Q
R
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
13.3
60
0
N.A.
6.6
0
N.A.
N.A.
20
N.A.
13.3
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
13.3
80
6.6
N.A.
26.6
6.6
N.A.
N.A.
20
N.A.
26.6
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
28
10
10
0
0
0
0
10
0
10
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
10
0
0
0
28
0
10
0
0
10
0
10
% D
% Glu:
19
0
0
10
10
0
0
0
0
10
0
10
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
19
0
19
10
19
10
28
19
10
37
0
% G
% His:
10
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
10
19
0
10
19
10
10
0
19
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
37
10
0
19
19
28
19
10
28
19
10
10
10
% P
% Gln:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
10
% Q
% Arg:
28
19
19
19
19
28
19
0
28
10
0
0
10
10
28
% R
% Ser:
19
37
0
28
10
0
10
19
10
28
10
28
10
0
10
% S
% Thr:
0
0
10
10
10
19
10
0
10
0
10
10
10
10
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _