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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
2.73
Human Site:
S2263
Identified Species:
6
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S2263
H
M
A
H
R
Q
G
S
S
S
V
S
G
S
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
E2552
R
E
R
E
R
R
Q
E
R
G
R
S
Q
E
R
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
T2132
Q
T
P
N
R
Q
G
T
G
S
L
S
E
S
S
Dog
Lupus familis
XP_537779
2046
229120
E1814
C
R
R
E
R
R
Q
E
R
G
R
S
Q
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
M2135
G
L
G
T
D
L
S
M
T
T
Q
S
G
D
L
Rat
Rattus norvegicus
P54282
2212
251509
P1980
E
S
S
M
K
E
S
P
S
W
V
T
Q
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
R1958
S
F
N
F
E
C
L
R
R
Q
S
S
Q
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
G2068
L
S
T
T
T
Q
S
G
D
L
P
S
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1619
A
R
S
P
S
P
S
R
Y
G
G
H
L
S
R
Honey Bee
Apis mellifera
NP_001159376
1904
215872
P1672
V
R
H
P
S
R
S
P
S
L
R
H
S
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1734
S
H
S
P
S
S
R
R
R
D
R
H
R
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
13.3
40
13.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
20
60
20
N.A.
33.3
40
N.A.
N.A.
6.6
N.A.
13.3
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
10
0
0
0
19
10
% D
% Glu:
10
10
0
19
10
10
0
19
0
0
0
0
10
28
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
19
10
10
28
10
0
19
10
10
% G
% His:
10
10
10
10
0
0
0
0
0
0
0
28
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
10
0
0
0
10
10
0
0
19
10
0
10
0
10
% L
% Met:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
28
0
10
0
19
0
0
10
0
0
10
19
% P
% Gln:
10
0
0
0
0
28
19
0
0
10
10
0
37
0
0
% Q
% Arg:
10
28
19
0
37
28
10
28
37
0
37
0
10
10
37
% R
% Ser:
19
19
28
0
28
10
46
10
28
19
10
64
10
28
10
% S
% Thr:
0
10
10
19
10
0
0
10
10
10
0
10
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _