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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
3.03
Human Site:
S2273
Identified Species:
6.67
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S2273
V
S
G
S
P
A
P
S
T
S
G
T
S
T
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2562
R
S
Q
E
R
R
Q
P
S
S
S
S
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2142
L
S
E
S
S
I
P
S
V
S
D
T
S
T
P
Dog
Lupus familis
XP_537779
2046
229120
P1824
R
S
Q
E
R
R
Q
P
S
S
S
S
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
K2145
Q
S
G
D
L
P
S
K
D
R
D
Q
D
R
G
Rat
Rattus norvegicus
P54282
2212
251509
M1990
V
T
Q
R
A
Q
E
M
F
Q
K
T
G
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
L1968
S
S
Q
D
D
I
P
L
S
P
N
F
H
H
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
G2078
P
S
K
E
R
D
R
G
R
A
K
D
R
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1629
G
H
L
S
R
S
K
R
T
Q
L
P
Y
P
T
Honey Bee
Apis mellifera
NP_001159376
1904
215872
G1682
R
H
S
P
G
R
P
G
Y
D
H
H
G
H
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
V1744
R
H
R
G
P
D
Y
V
E
F
H
D
R
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
20
60
20
N.A.
13.3
20
N.A.
N.A.
13.3
N.A.
6.6
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
33.3
66.6
33.3
N.A.
13.3
26.6
N.A.
N.A.
20
N.A.
13.3
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
10
19
0
0
10
10
19
19
10
10
0
% D
% Glu:
0
0
10
28
0
0
10
0
10
0
0
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% F
% Gly:
10
0
19
10
10
0
0
19
0
0
10
0
19
0
10
% G
% His:
0
28
0
0
0
0
0
0
0
0
19
10
10
19
10
% H
% Ile:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
10
0
0
19
0
0
10
19
% K
% Leu:
10
0
10
0
10
0
0
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
0
10
19
10
37
19
0
10
0
10
0
10
19
% P
% Gln:
10
0
37
0
0
10
19
0
0
19
0
10
0
0
0
% Q
% Arg:
37
0
10
10
37
28
10
10
10
10
0
0
19
10
10
% R
% Ser:
10
64
10
28
10
10
10
19
28
37
19
19
37
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
19
0
0
28
0
28
10
% T
% Val:
19
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _