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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
4.55
Human Site:
S2299
Identified Species:
10
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S2299
S
T
P
R
P
H
V
S
Y
S
P
V
I
R
K
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2588
R
E
P
P
K
P
K
P
S
L
S
S
H
P
T
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2168
P
K
P
R
P
L
L
S
Y
S
S
L
I
R
H
Dog
Lupus familis
XP_537779
2046
229120
P1850
R
E
P
S
Q
P
K
P
S
L
S
S
H
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
H2171
H
H
H
H
H
H
H
H
P
P
A
P
D
R
D
Rat
Rattus norvegicus
P54282
2212
251509
S2016
N
S
Q
P
N
S
Q
S
V
E
M
R
E
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
D1994
V
M
A
V
A
G
L
D
S
S
K
A
H
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
E2104
H
H
G
S
L
D
K
E
H
Y
G
H
E
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
Q1655
S
P
S
P
A
R
L
Q
E
M
R
E
R
D
R
Honey Bee
Apis mellifera
NP_001159376
1904
215872
R1708
S
N
V
V
E
I
Q
R
H
T
H
H
P
H
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
S1770
P
E
R
S
G
G
S
S
H
R
R
P
S
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
6.6
53.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
6.6
66.6
6.6
N.A.
13.3
20
N.A.
N.A.
20
N.A.
13.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
19
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
10
10
19
% D
% Glu:
0
28
0
0
10
0
0
10
10
10
0
10
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
19
0
0
0
0
10
0
0
0
19
% G
% His:
19
19
10
10
10
19
10
10
28
0
10
19
28
10
19
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
10
0
0
10
0
28
0
0
0
10
0
0
10
10
% K
% Leu:
0
0
0
0
10
10
28
0
0
19
0
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
10
10
0
0
10
0
% M
% Asn:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
10
37
28
19
19
0
19
10
10
10
19
10
28
10
% P
% Gln:
0
0
10
0
10
0
19
10
0
0
0
0
0
0
0
% Q
% Arg:
19
0
10
19
0
10
0
10
0
10
19
10
10
37
10
% R
% Ser:
28
10
10
28
0
10
10
37
28
28
28
19
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
19
% T
% Val:
10
0
10
19
0
0
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
19
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _