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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
6.06
Human Site:
S2363
Identified Species:
13.33
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S2363
G
G
H
S
S
G
R
S
P
R
M
E
R
R
V
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
R2643
P
Q
T
P
L
T
P
R
P
S
I
T
Y
K
T
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2239
L
H
E
D
S
H
A
S
D
C
G
E
E
E
T
Dog
Lupus familis
XP_537779
2046
229120
R1905
P
Q
T
P
L
T
P
R
P
S
V
T
Y
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
S2226
G
S
P
A
P
S
T
S
G
T
S
T
P
R
R
Rat
Rattus norvegicus
P54282
2212
251509
S2071
L
S
T
I
S
D
T
S
P
M
K
R
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
H2049
N
G
S
L
P
S
L
H
R
S
S
W
Y
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
S2160
V
P
S
T
S
G
T
S
T
P
R
R
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
N1710
Q
L
K
P
T
N
I
N
F
P
K
L
N
A
S
Honey Bee
Apis mellifera
NP_001159376
1904
215872
S1763
E
Q
R
S
R
S
P
S
P
I
G
G
R
Q
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
E1825
R
L
P
T
V
P
G
E
T
R
G
G
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
6.6
20
6.6
N.A.
20
20
N.A.
N.A.
6.6
N.A.
26.6
N.A.
0
26.6
N.A.
6.6
P-Site Similarity:
100
20
20
20
N.A.
26.6
20
N.A.
N.A.
6.6
N.A.
33.3
N.A.
13.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
10
% D
% Glu:
10
0
10
0
0
0
0
10
0
0
0
19
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
19
19
0
0
0
19
10
0
10
0
28
19
19
10
10
% G
% His:
0
10
10
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
19
0
0
19
0
% K
% Leu:
19
19
0
10
19
0
10
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% N
% Pro:
19
10
19
28
19
10
28
0
46
19
0
0
10
0
10
% P
% Gln:
10
28
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
10
0
10
0
10
19
10
19
10
19
19
28
19
% R
% Ser:
0
19
19
19
37
28
0
55
0
28
19
0
10
0
19
% S
% Thr:
0
0
28
19
10
19
28
0
19
10
0
28
0
10
28
% T
% Val:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _