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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1A All Species: 0
Human Site: S2412 Identified Species: 0
UniProt: O00555 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00555 NP_001120693.1 2505 282365 S2412 H H G Y Y R G S D Y D E A D G
Chimpanzee Pan troglodytes XP_520396 2784 310342 P2692 Q R D P L S Q P L A P G S R I
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 P2288 R R R R R G G P G P G M M C G
Dog Lupus familis XP_537779 2046 229120 P1954 Q R D P L S Q P L A A S S R I
Cat Felis silvestris
Mouse Mus musculus P97445 2368 267629 R2275 A P P G G S P R G C R R A P R
Rat Rattus norvegicus P54282 2212 251509 G2120 R T S E R S L G R Y T D V D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 E2098 V E A V L I S E G L G R Y A K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690548 2303 262065 R2209 L P T P T S R R F S P T G P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 L1759 R E R D R E R L R D R D R D R
Honey Bee Apis mellifera NP_001159376 1904 215872 L1812 N K P S T L Q L K P A N I N F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 K1874 R N S G G G S K G D V R L Q M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55 55.9 54.6 N.A. 87.9 82.7 N.A. N.A. 35.9 N.A. 72.3 N.A. 43 44.4 N.A. 39.6
Protein Similarity: 100 63.5 66.3 63.4 N.A. 89.9 84.6 N.A. N.A. 50.4 N.A. 80 N.A. 53.9 55.4 N.A. 51.6
P-Site Identity: 100 0 13.3 0 N.A. 6.6 13.3 N.A. N.A. 0 N.A. 0 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 6.6 13.3 6.6 N.A. 6.6 20 N.A. N.A. 0 N.A. 0 N.A. 13.3 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 19 19 0 19 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % C
% Asp: 0 0 19 10 0 0 0 0 10 19 10 19 0 28 0 % D
% Glu: 0 19 0 10 0 10 0 10 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % F
% Gly: 0 0 10 19 19 19 19 10 37 0 19 10 10 0 19 % G
% His: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 19 % I
% Lys: 0 10 0 0 0 0 0 10 10 0 0 0 0 0 10 % K
% Leu: 10 0 0 0 28 10 10 19 19 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 0 19 19 28 0 0 10 28 0 19 19 0 0 19 0 % P
% Gln: 19 0 0 0 0 0 28 0 0 0 0 0 0 10 0 % Q
% Arg: 37 28 19 10 28 10 19 19 19 0 19 28 10 19 19 % R
% Ser: 0 0 19 10 0 46 19 10 0 10 0 10 19 0 0 % S
% Thr: 0 10 10 0 19 0 0 0 0 0 10 10 0 0 10 % T
% Val: 10 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 0 0 19 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _