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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
1.52
Human Site:
T2172
Identified Species:
3.33
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
T2172
E
R
S
L
G
R
Y
T
D
V
D
T
G
L
G
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2485
T
H
L
C
S
T
T
P
D
R
P
P
P
S
Q
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
L2062
L
R
L
S
A
H
R
L
N
S
D
S
G
H
K
Dog
Lupus familis
XP_537779
2046
229120
A1747
H
V
A
H
L
C
N
A
A
L
D
R
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
S2068
G
N
D
L
S
T
I
S
D
T
S
P
M
K
R
Rat
Rattus norvegicus
P54282
2212
251509
I1913
K
I
Y
A
A
M
M
I
M
E
Y
Y
R
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
R1891
D
S
M
L
S
G
N
R
H
V
Y
D
Y
H
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
A2001
N
S
P
M
K
R
S
A
S
S
L
G
H
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
S1552
P
S
L
R
H
N
G
S
P
L
A
R
S
P
S
Honey Bee
Apis mellifera
NP_001159376
1904
215872
G1605
G
R
G
K
M
T
V
G
K
I
Y
V
C
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
K1667
R
D
R
D
E
R
G
K
G
G
P
V
D
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
6.6
20
6.6
N.A.
13.3
0
N.A.
N.A.
13.3
N.A.
6.6
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
6.6
33.3
20
N.A.
20
6.6
N.A.
N.A.
20
N.A.
13.3
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
19
0
0
19
10
0
10
0
10
0
10
% A
% Cys:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
10
% C
% Asp:
10
10
10
10
0
0
0
0
28
0
28
10
10
0
0
% D
% Glu:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
10
10
19
10
10
10
0
10
19
10
10
% G
% His:
10
10
0
10
10
10
0
0
10
0
0
0
10
19
0
% H
% Ile:
0
10
0
0
0
0
10
10
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
0
0
10
10
0
0
0
0
10
10
% K
% Leu:
10
0
28
28
10
0
0
10
0
19
10
0
0
19
10
% L
% Met:
0
0
10
10
10
10
10
0
10
0
0
0
10
0
0
% M
% Asn:
10
10
0
0
0
10
19
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
10
10
0
19
19
10
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
10
28
10
10
0
28
10
10
0
10
0
19
10
10
28
% R
% Ser:
0
28
10
10
28
0
10
19
10
19
10
10
10
10
19
% S
% Thr:
10
0
0
0
0
28
10
10
0
10
0
10
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
19
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
0
28
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _